Management of severe malaria cases learnings and challenges from the field (Publications)
A presentation on the management of severe malaria cases learnings and challenges from the field by Manuel Hetzel of the CARAMAL project.
Evaluating putative repellent 'push' and attractive 'pull' components for manipulating the odour orientation of host-seeking malaria vectors in the... (Publications)
BACKGROUND: Novel malaria vector control approaches aim to combine tools for maximum protection. This study aimed to evaluate novel and re-evaluate existing putative repellent 'push' and attractive 'pull' [...] 'pull' components for manipulating the odour orientation of malaria vectors in the peri-domestic space. METHODS: Anopheles arabiensis outdoor human landing catches and trap comparisons were implemented in [...] components led to a better understanding of their ability to affect...
Nanotechnological immunoassay for rapid label-free analysis of candidate malaria vaccines (Publications)
Malaria is a life-threatening epidemic disease with half of the world's population at risk. Although its incidence rate has fallen since 2010, this ratio dramatically stalled between 2014 and 2018. New [...] molecules in serum samples. The immunoassay successfully diagnoses humoral immune responses induced by malaria vaccine candidates and reveals the timeline and stage of the infection. We applied the newly developed [...] antibody/vaccine solutions, to blood samples from clinical trials on...
Communities and clinical trials: a case study from the RTS,S malaria vaccine trials in eastern Africa (Publications)
resource scarcity can intensify existing inequities. Here we present a case study of a phase III malaria vaccine clinical trial. Through qualitative interviews with researchers and caregivers of pediatric
Incorporating operational research in programmes funded by the Global Fund to Fight AIDS, Tuberculosis and Malaria in four sub-Saharan African... (Publications)
situation analysis of the extent to which grants from the Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund) are being utilized to support operational research and implementation research (OR/IR) [...] both via telephone/online conference tools and in person in four countries with a high burden of malaria and tuberculosis. These countries were Ghana, Sierra Leone, the United Republic of Tanzania and Zimbabwe
Patterns of pesticide usage in agriculture in rural Tanzania call for integrating agricultural and public health practices in managing... (Publications)
and malaria vector control, poor pesticide management practices and low-levels of awareness among farmers and pesticides retailers might enhance the selection of insecticide resistance in malaria vectors
PfMAP-2 is essential for male gametogenesis in the malaria parasite<em> Plasmodium falciparum</em> (Publications)
In malaria parasites, male gametogenesis is a proliferative stage essential for parasite transmission to the mosquito vector. It is a rapid process involving three rounds of genome replication alternating [...] induction of axoneme motility. However, in P. falciparum, causing the most severe form of human malaria, PfMAP-2 was suggested to be essential for asexual proliferation indicating distinct functions for
Correction to: Methods and indicators for measuring patterns of human exposure to malaria vectors (Publications)
An amendment to this paper has been published and can be accessed via the original article.
Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults (Publications)
(Pf) sporozoites (PfSPZ Vaccine) and protective efficacy assessed by homologous controlled human malaria infection (CHMI). Serum immunoglobulin G (IgG) responses were analyzed longitudinally using a Pf [...] first insights into naturally acquired and PfSPZ Vaccine-induced whole parasite antibody profiles in malaria pre-exposed Africans. Immunoreactivity was identified against 2,239 functionally diverse Pf proteins