Frédéric Tripet (People)
https://www.swisstph.ch/fr/staff/profile/people/frederic-tripet
facilities at the Malaria Research and Training center in Mali, West Africa. From 2018-2023 F. Tripet was a partner and field entomology technical coordinator on the Target Malaria consortium, a not- [...] and focus on the applied integrative biology of mosquitoes that transmit human pathogens, such as Malaria, Dengue, Chikungunya and Zika, with a view on developing novel tools for their control. From 2008 [...] that aims to develop new approaches to sterile male mosquito releases to reduce the...
Mechanistic within-host models of the asexual <em>Plasmodium falciparum</em> infection: a review and analytical assessment (Publications)
the last 30 years, several mechanistic mathematical models of malaria parasite within-host dynamics have been published and used in malaria transmission models. METHODS: Mechanistic within-host models of [...] and inter-individual variability. RESULTS: The assessed within-host malaria models generally replicate infection dynamics in malaria-naive individuals. However, there are substantial differences between [...] BACKGROUND: Malaria blood-stage infection length and intensity are important...
Comparison of a new IgG-EIA for the detection of anti-plasmodium antibodies with two currently used assays (Publications)
Material and Methods: In the present study two routine Plasmodium spp. ELISA (CAPTIA™ Malaria EIA, Trinity Biotech, and Malaria EIA, Bio-Rad) were compared with a new commercial ELISA (ELISA IgG, EUROIMMUN). [...] Conclusion: The comparison of the new EUROIMMUN ELISA and the established CAPTIA™ Malaria EIA (Trinity Biotech) and Ma-laria EIA (BioRad) used for routine blood donor screening in two laboratory blood donation [...] Background: Malaria is a mosquito-borne infectious disease caused by...
Creating an "enabling environment" for taking insecticide treated nets to national scale: the Tanzanian experience (Publications)
of its population at high risk of malaria by 2005. The country is, therefore, determined to ensure that sustainable malaria control using insecticide-treated nets is carried out on a national scale. CASE [...] INTRODUCTION: Malaria is the largest cause of health services attendance, hospital admissions and child deaths in Tanzania. At the Abuja Summit in April 2000 Tanzania committed itself to protect 60% of [...] been involved for two decades in the research process for developing...
Creating an "enabling environment" for taking insecticide treated nets to national scale: the Tanzanian experience (Publications)
of its population at high risk of malaria by 2005. The country is, therefore, determined to ensure that sustainable malaria control using insecticide-treated nets is carried out on a national scale. CASE [...] INTRODUCTION: Malaria is the largest cause of health services attendance, hospital admissions and child deaths in Tanzania. At the Abuja Summit in April 2000 Tanzania committed itself to protect 60% of [...] been involved for two decades in the research process for developing...
Melissa Penny speaks about the beauty of disease modelling (Blog)
https://www.swisstph.ch/fr/impact-stories/the-beauty-of-disease-modelling/blog-id/25
disease modelling for over 15 years. She joins us today to discuss the first malaria vaccine, disease modelling and the future of malaria eradication.
Distribution of survival times of deliberate <em>Plasmodium falciparum</em> infections in tertiary syphilis patients (Publications)
has important implications for mathematical modelling of malaria, which has for the past century exclusively assumed that the duration of malaria infections has an exponential distribution. It is desirable [...] influences the length of monitoring needed in an intervention programme for eliminating or reducing malaria
Distribution of survival times of deliberate <em>Plasmodium falciparum</em> infections in tertiary syphilis patients (Publications)
has important implications for mathematical modelling of malaria, which has for the past century exclusively assumed that the duration of malaria infections has an exponential distribution. It is desirable [...] influences the length of monitoring needed in an intervention programme for eliminating or reducing malaria
A multiplex qPCR approach for detection of <em>pfhrp2 </em>and <em>pfhrp3</em> gene deletions in multiple strain infections of <em>Plasmodium... (Publications)
The rapid and accurate diagnosis of Plasmodium falciparum malaria infection is an essential factor in malaria control. Currently, malaria diagnosis in the field depends heavily on using rapid diagnostic [...] blood. P. falciparum strains lacking PfHRP2, due to pfhrp2 gene deletions, are an emerging threat to malaria control programs. The novel assay described here, named qHRP2/3-del, is well suited for high-throughput
Antimalarial efficacy of MMV390048, an inhibitor of <em>Plasmodium</em> phosphatidylinositol 4-kinase (Publications)
of MMV390048 to block all life cycle stages of the malaria parasite suggests that this compound should be further developed and may contribute to malaria control and eradication as part of a single-dose [...] As part of the global effort toward malaria eradication, phenotypic whole-cell screening revealed the 2-aminopyridine class of small molecules as a good starting point to develop new antimalarial drugs [...] we found that the derivative, MMV390048, lacked cross-resistance with current drugs...