Effects of changing mosquito host searching behaviour on the cost effectiveness of a mass distribution of long-lasting, insecticidal nets: a modelling... (Publications)
BACKGROUND: The effectiveness of long-lasting, insecticidal nets (LLINs) in preventing malaria is threatened by the changing biting behaviour of mosquitoes, from nocturnal and endophagic to crepuscular [...] stochastic simulation models, we studied the impact of a mass LLIN distribution on Plasmodium falciparum malaria. Specifically, we looked at impact in terms of episodes prevented during the effective life of the [...] occur within the same mosquito population. LLINs are likely cost effective...
Infection and co-infection with helminths and <em>Plasmodium</em> among school children in Côte d'Ivoire: results from a national cross-sectional... (Publications)
Helminth infection and malaria remain major causes of ill-health in the tropics and subtropics. There are several shared risk factors (e.g., poverty), and hence, helminth infection and malaria overlap geographically [...] provide a rationale to combine control interventions that simultaneously aim at helminthiases and malaria
The development of an ivermectin-based attractive toxic sugar bait (ATSB) to target <em>Anopheles arabiensis</em> (Publications)
Africa are moving towards malaria-elimination, mostly thanks to successful vector control campaigns. However, elimination has proven challenging, resulting in the persistence of malaria transmission. It is now [...] now accepted that in order to eliminate malaria, new complementary vector control approaches must be developed. This study describes the development of a sugar-baited resting place containing a toxic dose
Molecular methods for tracking residual <em>Plasmodium falciparum </em>transmission in a close-to-elimination setting in Zanzibar (Publications)
essential for surveillance studies conducted to inform malaria control strategies in close-to-elimination settings. Molecular monitoring of residual malaria infections usually requires a large study size, therefore [...] screening large sample sets represents primarily a research tool that should inform the design of malaria elimination strategies. It may also prove beneficial for diagnostic tasks in surveillance-response
Surveillance of molecular markers of <em>Plasmodium falciparum</em> artemisinin resistance (<em>kelch</em>13 mutations) in Papua New Guinea between... (Publications)
Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene (Pfk13) that are associated [...] in other parts of PNG is unknown. We investigated the prevalence of Pfk13 mutations in multiple malaria-endemic regions of PNG. P. falciparum isolates (n = 1152) collected between 2016 and 2018 and assessed [...] Continued surveillance for molecular markers of drug resistance is...
Basel vaccine research and development initiative (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/basel-vaccine-research-and-development-initiative
tropics by addressing current needs in vaccines research and development. First targets will be malaria and Buruli ulcer, two infectious diseases which affect primarily children in Africa.
Basel vaccine research and development initiative (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/basel-vaccine-research-and-development-initiative
tropics by addressing current needs in vaccines research and development. First targets will be malaria and Buruli ulcer, two infectious diseases which affect primarily children in Africa.
Massive Open Online Course on Insecticide Resistance Management (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/massive-open-online-course-on-insecticide-resistance-management
the authoritative resource for Insecticide Resistance Management (IRM) in the mosquito vectors of malaria. However, IRM is an applied science, and there is a need to translate theory into practice. Whilst [...] to anyone, but will be specifically designed for, and promoted to, those involved with practical malaria vector control. <!-- [if gte mso 9]> <
Synthesis and structure-activity relationships of new 2-phenoxybenzamides with antiplasmodial activity (Publications)
The 2-phenoxybenzamide 1 from theMedicines for Malaria Venture Malaria Box Project has shown promising multi-stage activity against different strains of P. falciparum. It was successfully synthesized via
In vitro antiprotozoal activities and cytotoxicity of some selected Cameroonian medicinal plants (Publications)
Eight extracts from seven selected Cameroonian medicinal plants, traditionally used to treat malaria and other protozoal diseases, were tested in vitro for their antiprotozoal activities against Plasm [...] Leishmania donovani, Trypanosoma cruzi and Trypanosoma brucei rhodesiense, protozoa responsible for malaria, visceral leishmaniasis, Chagas disease and African trypanosomiasis, respectively. The most active
