Discovery of dual function acridones as a new antimalarial chemotype (Publications)
resistance, and both are undesirable in effective long-term strategies against multi-drug-resistant malaria. Haem remains an immutable and vulnerable target, because it is not parasite-encoded and its det
Blood-stage parasitaemia and age determine <em>Plasmodium falciparum</em> and <em>P. vivax</em> gametocytaemia in Papua New Guinea (Publications)
A better understanding of human-to-mosquito transmission is crucial to control malaria. In order to assess factors associated with gametocyte carriage, 2083 samples were collected in a cross-sectional
The epidemiology of multiple <em>Plasmodium falciparum</em> infections. 9. Effect of insecticide-treated bed nets on haemoglobin values, prevalence... (Publications)
randomized controlled trial of insecticide-treated bed nets (ITNs) was conducted in an area of high malaria transmission in Tanzania in order to assess the effects of ITNs on infection and anaemia. One hundred
A microarray-based system for the simultaneous analysis of single nucleotide polymorphisms in human genes involved in the metabolism of anti-malarial... (Publications)
BACKGROUND: In order to provide a cost-effective tool to analyse pharmacogenetic markers in malaria treatment, DNA microarray technology was compared with sequencing of polymerase chain reaction (PCR)
More than seven decades of <em>Acta Tropica</em>: looking back to move into the future (Publications)
surveillance, control, and elimination of diseases that are intimately linked to poverty, such as malaria and neglected tropical diseases. In recent years, the scope of Acta Tropica was widening to target
Time to scale up molecular surveillance for anti-malarial drug resistance in sub-Saharan Africa (Publications)
emergence of resistance. However, molecular markers are not monitored systematically by national malaria control programmes, and are often assessed in research studies, but not in routine surveillance.
<em>P. falciparum</em> and <em>P. vivax</em> orthologous coiled-coil candidates for a potential cross-protective vaccine (Publications)
Over the last four decades, significant efforts have been invested to develop vaccines against malaria. Although most efforts are focused on the development of P. falciparum vaccines, the current availability
Influence of sugar availability and indoor microclimate on survival of <em>Anopheles gambiae</em> (Diptera: Culicidae) under semifield conditions in... (Publications)
served to increase survival potential of vectors beyond ages at which they are old enough to transmit malaria
Variation in calculating and reporting antimalarial efficacy against<em> Plasmodium falciparum</em> in sub-Saharan Africa: a systematic review of... (Publications)
artemisinin-based combination therapies (ACTs), are critical tools in reducing the global burden of malaria, which is concentrated in sub-Saharan Africa. Performing and reporting antimalarial efficacy studies
Emergence of artemisinin-resistant <em>Plasmodium falciparum</em> with <em>kelch13 </em>C580Y mutations on the island of New Guinea (Publications)
nt Plasmodium falciparum carrying the C580Y mutation in the kelch13 gene is a growing threat to malaria elimination in Southeast Asia, but there is no evidence of their spread to other regions. We conducted