Interventions that effectively target <em>Anopheles funestus</em> mosquitoes could significantly improve control of persistent malaria transmission in... (Publications)
Malaria is transmitted by many Anopheles species whose proportionate contributions vary across settings. We re-assessed the roles of Anopheles arabiensis and Anopheles funestus, and examined potential [...] potential benefits of species-specific interventions in an area in south-eastern Tanzania, where malaria transmission persists, four years after mass distribution of long-lasting insecticide-treated nets (LLINs) [...] arabiensis (44.1%). Though An. arabiensis is still the most abundant vector...
The economics of malaria control and elimination: a systematic review (Publications)
cost of malaria control to a health system ranged from $0.11 to $39.06 (median: $2.21) while that for malaria elimination ranged from $0.18 to $27 (median: $3.00). BCRs of investing in malaria control [...] competing health priorities threaten the sustainability of malaria programmes. Elucidating the cost and benefits of continued investments in malaria could encourage sustained political and financial commitments [...] financial cost and return of malaria control, elimination and eradication....
Asymptomatic and sub-microscopic malaria infection in Kayah State, eastern Myanmar (Publications)
be targeted for malaria elimination. METHODS: A mass blood survey was conducted among 485 individuals from six villages in Kayah State, an area of endemic but low transmission malaria in eastern Myanmar [...] BACKGROUND: Myanmar has the heaviest burden of malaria in the Greater Mekong Sub-region. Asymptomatic Plasmodium spp. infections are common in this region and may represent an important reservoir of t [...] Myanmar. Malaria infection was screened by rapid diagnostic test (RDT), light...
Mefloquine at the crossroads? Implications for malaria chemoprophylaxis in Europa [Commentary] (Publications)
mefloquine. Some malaria prevention advisors question the scientific basis for the restrictions and suggest that this cost-effective, anti-malarial drug will be displaced as a first-line anti-malaria medication [...] the new recommendations for malaria prophylaxis that have been adapted by Switzerland, Germany, Austria and Italy where chemoprophylaxis use is restricted to high-risk malaria-endemic areas. [...] Since its introduction to the market in 1985, mefloquine has been used for malaria...
Immuno-gold silver staining assays on capillary-driven microfluidics for the detection of malaria antigens (Publications)
a lack of highly sensitive malaria RDTs that can detect low antigen concentration at the onset of infection. Here, we present a strategy to improve the sensitivity of malaria RDTs by using capillary-driven [...] al to the concentration of antigen in a sample. We illustrate this method using the recombinant malaria antigen Plasmodium falciparum histidine-rich-protein 2 (rPfHRP2) spiked in human serum. This antigen [...] min, which is approaching the desired sensitivity needed in the Target...