Structure, biosynthesis, and bioactivity of photoditritide from <em>Photorhabdus temperata</em> Meg1 (Publications)
A new cyclic peptide photoditritide (1), containing two rare amino acid d-homoarginine residues, was isolated from Photorhabdus temperata Meg1 after the nonribosomal peptide synthetase encoding gene p
Socio-economic inequality and inequity in use of health care services in Kenya: evidence from the fourth Kenya household health expenditure and... (Publications)
BACKGROUND: Kenya is experiencing persistently high levels of inequity in health and access to care services. In 2018, decades of sustained policy efforts to promote equitable, affordable and quality
One hundred years of Suramin (Publications)
Suramin is a hundred years old and still being used to treat the first stage of acute human sleeping sickness, caused by Trypanosoma brucei rhodesiense Suramin is a multifunctional molecule with a wid
Antibiotic exposure among children younger than 5 years in low-income and middle-income countries: a cross-sectional study of nationally... (Publications)
BACKGROUND: Antibiotic resistance is a major threat to global health. Although detailed information about antibiotic use in high-income countries is available, little is known regarding the use of ant
Impact of changes in detection effort on control of visceral leishmaniasis in the Indian subcontinent (Publications)
BACKGROUND: Control of visceral leishmaniasis (VL) on the Indian subcontinent relies on prompt detection and treatment of symptomatic cases. Detection efforts influence the observed VL incidence and h
Strengthening surveillance systems for malaria elimination by integrating molecular and genomic data (Publications)
Unprecedented efforts in malaria control over the last 15 years have led to a substantial decrease in both morbidity and mortality in most endemic settings. However, these progresses have stalled over
Antiprotozoal activity of Turkish <em>Origanum onites</em> essential oil and its components (Publications)
Essential oil of Origanum species is well known for antimicrobial activity, but only a few have been evaluated in narrow spectrum antiprotozoal assays. Herein, we assessed the antiprotozoal potential
Increased detection of invasive enteropathogenic bacteria in pre-incubated blood culture materials by real-time PCR in comparison with automated... (Publications)
BACKGROUND: Invasive enteropathogenic bacteria can cause systemic infections. Data from studies with PCR detection suggest, at least for Salmonella enterica, that blood culture may lead to underestima
16S rRNA gene sequence-based identification of bacteria in automatically incubated blood culture materials from tropical sub-Saharan Africa (Publications)
BACKGROUND: The quality of microbiological diagnostic procedures depends on pre-analytic conditions. We compared the results of 16S rRNA gene PCR and sequencing from automatically incubated blood cult
Rapid discrimination of <em>Haemophilus influenzae</em>, <em>H. parainfluenzae</em>, and<em> H. haemolyticus</em> by fluorescence<em> in situ</em>... (Publications)
BACKGROUND: Due to considerable differences in pathogenicity, Haemophilus influenzae, H. parainfluenzae and H. haemolyticus have to be reliably discriminated in routine diagnostics. Retrospective anal
