Efficacy of drugs against clonorchiasis and opisthorchiasis: a systematic review and network meta-analysis (Publications)
for 5 days and 400 mg twice a day for 7 days) resulted in cure rates of 100%, while two other multiple-dose regimens of albendazole resulted in high predicted cure rates: 300 mg twice a day for 5 days [...] praziquantel regimen (25 mg/kg three times a day for 2 days) also showed a high predicted cure rate (98.5% [85.4-99.9]) in C sinensis infection, and predicted cure rates were above 90% for several other mu [...] including 20 mg/kg three times a day for 3 days (97.6% [74.7-99.8]), 14 mg/kg...
Spatial-temporal and cancer risk assessment of selected hazardous air pollutants in Seattle (Publications)
HAPs. The median values of the estimated inhalation cancer risks ranged between 4.3x10(-5) and 6.0x10(-5), with the 5th and 95th percentile levels exceeding the 1 in a million level. VOCs as a whole contributed
Transmission dynamics of highly pathogenic avian influenza at lake constance (Europe) during the outbreak of winter 2005-2006 (Publications)
Highly pathogenic avian influenza virus (HPAI) H5N1 poses a serious threat to domestic animals. Despite the large number of studies on influenza A virus in waterbirds, little is still known about the [...] and spread of these viruses in the wild waterbird population. From January to April 2006, the HPAI H5N1 virus was confirmed in 82 dead wild waterbirds at the shores of Lake Constance. In this study, we [...] at the end of the winter. With this study, we quantify for the first time the...
Discordances in the application of different criteria for quantification of paediatric abdominal obesity: an analysis of two Swiss studies (Publications)
abdominal obesity varied between 3.1 and 49.4% in boys, and 4.7 and 55.5% in girls (Ballabeina), and between 1.8 and 36.3% in boys and 4.5 and 37.3% in girls (KISS). Among children considered as abdominally [...] 190 girls and 162 boys (Ballabeina), and from 134 girls and 113 boys (Kinder-Sportstudie, KISS) aged 5-11 years were used. TBF was assessed by bioimpedance (Ballabeina) or dual energy X-ray absorption (KISS)
Antiprotozoal isoflavan quinones from <em>Abrus precatorius</em> ssp. <em>africanus</em> (Publications)
and three isoflavan quinones, abruquinone I (3), abruquinone B (4), and 7,8,3''5'-tetramethoxyisoflavan-1',4'-quinone (5). Compounds 1 and 3 were new natural products. The absolute configuration of compounds [...] values of 0.30 and 0.16 microM, respectively) and good selectivity (selectivity indices of 73.7 and 50.5, respectively)
Assessing health risk due to exposure to arsenic in drinking water in Hanam province, Vietnam (Publications)
tube-well water for drinking purpose were 25.3 × 10-5 (using only well water) and 7.6 × 10-5 (using both well and rain water). The skin cancer risk would be 11.5 times higher if the water was not filtered. I
New antiparasitic flexible triaryl diamidines, their prodrugs and aza analogues: synthesis, <em>in vitro</em> and<em> in vivo</em> biological... (Publications)
of > 60 days upon a 4 × 5 mg/kg dose i. p. treatment. Moreover, thermal melting analysis measurement ΔT(m) for this series of diamidines/poly (dA-dT) complexes fell between 0.5 and 19 °C with 6c showing [...] amidines (6a-c, 13a,b and 17), their aza analogues (23 and 27) and respective methoxyamidine prodrugs (5, 7, 12a,b, 22 and 26). All diamidines were assessed in vitro against Trypanosoma brucei rhodesiense
Incidence and predictors of immune reconstitution inflammatory syndrome in a rural area of Mozambique (Publications)
patients developed IRIS [26.5%, incidence rate 3.1 cases/100 persons-month of ART (95% CI 2.2-4.3)]. Median time to IRIS onset was 62 days from ART initiation (IQR 35.5-93.5). Twenty-five cases (69.4%)
Evaluation of standard field and laboratory methods to compare protection times of the topical repellents PMD and DEET (Publications)
in the AIC test were 0.5, 2 and 2 hours against Ae. aegypti, An. stephensi and Cx. quinquefasciatus, respectively, and the corresponding median CPTs for PMD were 0.5, 1 and 0.5 hours. In conclusion, DEET
Cross-sectional serological survey for <em>Leptospira spp.</em> in beef and dairy cattle in two districts in Uganda (Publications)
9-24.5%). Pomona seroprevalence was highest with 9.45% (6.4-13.7%), followed by Kenya 5.09% (2.9-8.6%), Nigeria 4.00% (2.1-7.2%), Wolfii 3.27% (1.6-6.3%), Butembo 1.86% (0.7-4.4%), Hardjo 1.45% (0.5-3.9%)