Dolutegravir in real life: self-reported mental and physical health outcomes after transitioning from efavirenz- to dolutegravir-based antiretroviral... (Publications)
median age was 46 years (interquartile range [IQR] 38-55), and the median time taking ART was 5.7 years (IQR 3.5-8.9). No change was observed for weight or overall PHQ-9 or SF-12 outcomes. However, three [...] , strange/vivid dreams' (6.3% vs. 3.5%; adjusted p = 0.027). Individual PHQ-9 or SF-12 items also improved. Being symptom free across all measures increased from 5.1% to 11.4% (p < 0.0001). CONCLUSIONS:
Community-based wound management in a rural setting of Côte d'Ivoire (Publications)
age was 10 years (IQR 7-15), 63.0% of patients were male. Almost all (99.5%, 870/874) wounds closed within the observation period, 5.3% (49/923) were lost to follow-up. Wounds primarily treated in C, HC and [...] and DH presented with secondary bacterial infections in 10.3% (36/350), 31.0% (133/429) and 100% (5/5) of cases, respectively. Recapturing was required in 68.3% (630/923) of wounds with participants reporting
Dynamics and risk of transmission of bovine tuberculosis in the emerging dairy regions of Ethiopia (Publications)
apparent prevalence of bTB, as measured by the SICCT test, was 4.5% (95% CI 3.7-5.4%) at the individual animal-level and 24% (95% CI 17.5-32%) at the herd-level. There was no statistically significant change [...] consistent with the infection being endemic. The incidence rate was estimated at 3.6 (95% CI 2.8-4.5) and 6.6 (95% CI 3.0-12.6) cases/100 cattle (or herd)-years at the animal- and herd-levels, respectively
Europe-wide high-spatial resolution air pollution models are improved by including traffic flow estimates on all roads (Publications)
models for NO2, PM10, PM2.5, and O3, especially for NO2 (3% improvement of geographically-weighted regression model). Improvement of model performance was larger in urban areas (5% and 8% increases in R2 [...] annual average daily traffic (AADT) from six European countries. We evaluated our AADT models using 5-fold cross-validation (CV) and by comparison of our Europe-wide traffic flow estimates with national [...] improved the performance of the models based upon major road length in different...
International study of childhood leukemia in residences near electrical transformer rooms (Publications)
were 1.0 (95% CI: 0.5, 1.9) for intermediate and 1.1 (95% CI: 0.3, 3.8) for high exposure in the conditional logistic model. In the mixed logistic model, RRs were 1.4 (95% CI: 0.8, 2.5) for intermediate [...] buildings with built-in electrical transformers. ELF-MF in apartments above built-in transformers can be 5 times higher than in other apartments in the same building. This novel study design aimed to maximize [...] 1.3 (95% CI: 0.4, 4.4) for high. Data of the most influential country showed...
The effectiveness of community health worker training, equipping, and deployment in reducing COVID-19 infections and deaths in rural Western Kenya: a... (Publications)
(the mean monthly CHW household visits in Siaya was 146,648.5, standard deviation 11,066.5 versus 42,644.5 in Kisii, standard deviation 899.5, p value = 0.01). Deploying trained and equipped CHWs in rural
Long-term exposure to airborne metals and risk of cancer in the French cohort Gazel (Publications)
specific compounds that make ambient fine particulate matter (PM2.5) carcinogen remain poorly identified. Some metals contribute to ambient PM2.5 and possibly to its adverse effects. But the challenge of assessing [...] findings were consistent across supplementary analyses, albeit attenuated when accounting for total PM2.5. Regarding specific site cancers, we estimated positive associations mostly for bladder, and generally [...] were associated with risk of cancer. These findings may help...
Temporal variations in the short-term effects of ambient air pollution on cardiovascular and respiratory mortality: a pooled analysis of 380 urban... (Publications)
PM(2·5), or NO(2) and mortality. However, the risk of cardiovascular mortality increased from 0·37% (95% CI -0·05 to 0·80) in 1998 to 0·85% (0·55 to 1·16) in 2012 with a 10 μg/m(3) increase in PM(2·5). [...] BACKGROUND: Ambient air pollution, including particulate matter (such as PM(10) and PM(2·5)) and nitrogen dioxide (NO(2)), has been linked to increases in mortality. Whether populations' vulnerability [...] database. We applied a two-stage approach to analyse the short-term effects of...
Effect of strategic gastrointestinal nematode control on growth of N'Dama cattle in Gambia (Publications)
treatment on liveweights was found in 5-year-old and older animals. Herd structure analysis demonstrated that overall male offtake rates ranged from 12 to 28% in the 3-, 4- and 5-year-old age categories. The age [...] One group received a single anthelmintic treatment of Fenbendazole, Panacur Hoechst Veterinar GmbH, 7.5 mg kg-1 BW in October 1989, whereas the other group served as an untreated control. In July 1990, the [...] treatments significantly increased liveweights of the age group 12-24...
Air pollution and cardiovascular mortality with over 25 years follow-up: a combined analysis of two British cohorts (Publications)
[95% CI: 0.70-1.92] for PM10 and 1.30 [95% CI: 0.39-4.34] for PM2.5, with largest effects seen in the fourth quartile of BS and PM2.5 compared to the first with HR 1.24 [95% CI: 0.91-1.61] and 1.21 [95% [...] Pollution (ESCAPE), air pollution estimates in 2010-11 were obtained for NO2, NOx, PM10, PMcoarse and PM2.5. The exposure estimates were assigned to place of residence 1989 for participants in a national birth [...] non-significant hazard ratios for CVD mortality were seen with 1991 BS and...