Dynamics and risk of transmission of bovine tuberculosis in the emerging dairy regions of Ethiopia (Publications)
apparent prevalence of bTB, as measured by the SICCT test, was 4.5% (95% CI 3.7-5.4%) at the individual animal-level and 24% (95% CI 17.5-32%) at the herd-level. There was no statistically significant change [...] consistent with the infection being endemic. The incidence rate was estimated at 3.6 (95% CI 2.8-4.5) and 6.6 (95% CI 3.0-12.6) cases/100 cattle (or herd)-years at the animal- and herd-levels, respectively
Prospective risk of morbidity in relation to multiplicity of infection with <em>Plasmodium falciparum </em>in Sao Tomé (Publications)
initial cross-sectional survey, 40.5% of individuals were recorded by microscopy as infected with P. falciparum, and by PCR 60.5%, with the maximum prevalence in children aged 5-10 years. PCR-RFLP typing of
Inflammatory response and IgE sensitization at early age (Publications)
concentrations (sIgE) at the age of one and 4.5 yr. Analyses were made by logistic regression analysis. RESULTS: The risk of allergic sensitization at the age of 4.5 yr was decreased in children who had increased [...] and the development of allergic sensitization, atopic dermatitis (AD), and asthma at the age of 4.5 yr. METHODS: We studied 636 children participating in the PASTURE study in Finland, Germany, Austria
Evaluation of land use regression models for NO2 and particulate matter in 20 European study areas: the ESCAPE project (Publications)
correlation between concentrations of PM metrics and NO2. LUR models have been developed for NO2, PM2.5 absorbance and Copper (Cu) in PM10 based on 20 sites in each of the 20 study areas of the ESCAPE project [...] concentrations with measured NO2 concentrations at the 20 additional NO2 sites in each area. For NO2, PM2.5 absorbance and PM10 Cu, the median LOOCV R2s were 0.83, 0.81 and 0.76 whereas the median HEV R2 were [...] were 0.52, 0.44 and 0.40. There was a positive association between the...
Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds from <em>Allanblackia monticola</em> and <em>Symphonia globulifera</em> (Publications)
xanthones: allanxanthone A (5), xanthone V-1 (6) and globulixanthone C (7) as active constituents. Compounds 1 and 6 were isolated from S. globulifera leaves, while compounds 2-5 were obtained from A. monticola [...] guttiferone F (4) (IC50 = 2.77 and 3.50 mu M, respectively) were more active than galanthamine (ICSO = 8.5) against BChE
Can primary health care mitigate the effects of economic crises on child health in Latin America? An integrated multicountry evaluation and... (Publications)
of coverage of primary health care on mortality rates in children younger than 5 years (hereafter referred to as under-5 mortality) across different age groups and causes of death, adjusting for all relevant [...] previous longitudinal datasets with validated dynamic microsimulation models and projected trends in under-5 mortality rates under alternative policy response scenarios until 2030. FINDINGS: High primary health-care
The burden of surgical site infections and related antibiotic resistance in two geographic regions of Sierra Leone: a prospective study (Publications)
older. Of the 417 patients, 233 (55.9%) were enrolled in MGH. Most were women 294 (70.5%). The incidence rate of SSI was 5.5 per 1000 patient-days, and the cumulative incidence of SSI was 8.2%. Common bacteria
The influence of meteorological factors and atmospheric pollutants on the risk of preterm birth (Publications)
Cox models. The frequency of preterm birth was 5.0%. Preterm birth risk tended to increase with first-trimester average atmospheric pressure (odds ratio per 5-mbar increase = 1.06, 95% confidence interval: [...] some evidence of an increase in preterm birth risk with first-trimester average temperature in the -5 degrees C to 15 degrees C range, with a plateau afterwards (spline coding, P = 0.08). No evidence of
Potential impact of climate change on schistosomiasis: a global assessment attempt (Publications)
CMIPs are designed to improve the workings of the GCMs. We chose RCP4.5 which represented a medium GHG emission increase and CMIP5, the most recently completed CMIP phase. Combining this meteorological [...] Panel on Climate Change (IPCC) predicts that global, average temperatures will increase by at least 1.5 degrees C in the near future and more by the end of the century if greenhouse gases (GHGs) emissions
Transcriptomic and lipidomic profiles of glycerolipids during <em>Arabidopsis</em> flower development (Publications)
system to synchronize flower development in Arabidopsis. The transgenic plant PAP1::AP1-GR ap1-1 cal-5 showed synchronized flower development upon dexamethasone treatment, which enabled massive harvesting [...] nonphosphorous galactolipids during the late stage. Moreover, in the midstage, phosphatidylinositol 4,5-bisphosphate concentration was increased transiently, which suggests the stimulation of the phosphoinositide [...] of multiple phosphoinositide biosynthetic genes associated with the...