Representation of authors and editors from countries with different human development indexes in the leading literature on tropical medicine: survey... (Publications)
accounted for 5.0%. Our data indicate that research collaborations between a country with a high human development index and one that has either a medium or a low index are common and account for 26.5% and 16 [...] full articles published in the six leading journals on tropical medicine in 2000-2. RESULTS: Sixteen (5.1%) of the 315 editorial and advisory board members from the 12 ISI referenced journals on tropical
Relative contribution of day-to-day and intra-specimen variation in faecal egg counts of <em>Schistosoma mansoni</em> before and after treatment with... (Publications)
area in Cjte d'Ivoire highly endemic for S. mansoni. Stool specimens were collected over 5 consecutive days, and 5 egg-counts were made in each specimen by the Kato-Katz technique. The point prevalence of [...] of the first sample was 42.7% and the cumulative prevalence after the maximum sampling effort was 88.5%. Using generalized linear mixed models we found that the presence of S. mansoni eggs in a stool sample
Recombinant expression of trypanosome surface glycoproteins in <em>Pichia pastoris</em> for the diagnosis of <em>Trypanosoma evansi</em> infection (Publications)
Pichia (P.) pastoris. The M5 strain of this yeast has an engineered N-glycosylation pathway resulting in homogenous Man5GlcNAc2 N-glycosylation which resembles the predominant Man9-5GlcNAc2 oligomannose structures
A standardised method for interpreting the association between mutations and phenotypic drug resistance in <em>Mycobacterium tuberculosis</em> (Publications)
(93.1-95.5%), respectively. For second-line drugs, sensitivity varied from 67.4% (64.1-70.6%) for capreomycin to 88.2% (85.1-90.9%) for moxifloxacin, with specificity ranging from 90.0% (87.1-92.5%) for [...] moxifloxacin to 99.5% (99.0-99.8%) for amikacin.This study provides a standardised and comprehensive approach for the interpretation of mutations as predictors of M. tuberculosis drug-resistant phenotypes
Financially incentivized knowledge assessments to improve provider compliance with treatment guidelines: a cluster-randomized controlled trial (Publications)
BACKGROUND: Despite increasing access to health care, under-5 mortality remains high in many parts of Sub-Saharan Africa. Interventions to improve quality of care have mostly focused on additional training [...] chosen for this study. All health care workers providing outpatient services to children under age 5 in these facilities will be included in the study. Facilities were randomized with equal probability [...] financing to health care worker performance on knowledge assessments can...
Dioncophyllines C2, D2, and F and related naphthylisoquinoline alkaloids from the Congolese liana <em>Ancistrocladus ileboensis</em> with potent... (Publications)
Dioncophylline F (1), the first 5,8'-coupled dioncophyllaceous alkaloid (i.e., lacking an oxygen function at C-6 and possessing an R-configuration at C-3), was isolated from the recently described Congolese [...] semistable and, thus, slowly interconverting atropo-diastereomers, whereas dioncophylline C2 (2), with its 5,1'-linkage, is configurationally stable at the axis. Eight further known naphthylisoquinolines were [...] isolated from A. ileboensis, among them dioncophylline A (P-10), its...
Seroprevalence survey of brucellosis among rural people in Mongolia (Publications)
were being older than 45 years (adjusted odds ratio [AOR] = 6.9, 95% CI = 5.1-8.7) and being a veterinarian (AOR = 2.8, 95% CI = 1.5-5.0). CONCLUSION: Our study confirms that human brucellosis seroprevalence
Seroprevalence of Rift Valley fever, Q fever, and brucellosis in ruminants on the southeastern shore of Lake Chad (Publications)
and 10.8% (95% CI 3.0-18.5) in sheep. For brucellosis and Q fever, only cattle samples from islands were analyzed. For Q fever, the apparent seroprevalence was 7.8% (95% CI 5.6-10.1). For brucellosis, [...] the RBT showed a prevalence of 5.7% (95% CI 3.8-7.6), and ELISA showed 11.9% (95% CI 9.3-14.6) with a kappa value of 0.53 showing a moderate agreement between the two tests. This study confirms the presence
Heart rate variability and sleep-related breathing disorders in the general population (Publications)
population of young and healthy adults. Participants aged 25 to 41 years with a body mass index /=5 or an ODI > /=5. Multivariable regression models were constructed to assess the relation of HRV with either [...] AHI or ODI. Median age of the 1,255 participants was 37 years, 47% were men, and 9.6% had an AHI > /=5. Linear inverse associations of SDNN across AHI and ODI groups were found (p for trend = 0.006 and 0
Strengthening HIV therapy and care in rural Tanzania affects rates of viral suppression (Publications)
logistic regression. Results: This study included 304 participants with a median time on ART of 3.5 years (IQR = 1.7-5.3 years); 91% were on an NNRTI-based regimen and 9% were on a boosted PI-based regimen. Viral [...] successfully genotyped and 17/21 (81%) harboured > /=1 clinically relevant HIV-DRM. Of these, 13/17 (76.5%) had HIV-1 plasma viral loads of > 1000 copies/mL. CD4 cell count 8-fold increased odds of developing
