Antagonistic effects of <em>Plasmodium</em>-helminth co-infections on malaria pathology in different population groups in Côte d'Ivoire (Publications)
participants aged 5-16 years from a school-based study. CONCLUSIONS/SIGNIFICANCE: No exacerbation from co-infection with Plasmodium and helminths was observed, neither in participants aged 5-18 years nor in [...] of antagonistic nature but varied in magnitude and species combination. In study participants aged 5-18 years from community-based studies, Plasmodium-hookworm co-infection showed an antagonistic interaction
ExpoApp: an integrated system to assess multiple personal environmental exposures (Publications)
level between ExpoApp and reference tools was 86.6% (86.5-86.7) and 75.7% (71.5-79.4), respectively. ExpoApp estimated that participants inhaled 16.5x10(10) particles/day of UFP and had almost no contact
How within-city socioeconomic disparities affect life expectancy? Results of Urban HEART in Tehran, Iran (Publications)
SES. The e0 gender gap among districts was 5.5 years for females and 3.7 years for males. The highest and lowest mean of e0 observed in SC1 (highest class) and SC5 (lowest class), were 77.6 and 76.0 years
Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function (Publications)
meta-analysis produced suggestive evidence for association at the novel IL16/STARD5/TMC3 locus on chromosome 15 (P = 5.71 x 10-7). In addition, meta-analysis using the five cohorts with > /=3 FEV1 measurements [...] associated with FEV1 decline in two additional cohort studies. We confirmed gene expression of IL16, STARD5, and ME3 in multiple lung tissues. Publicly available microarray data confirmed differential expression
Étude du biais dû aux non-répondants dans une étude épidemiologique (SAPALDIA) (Publications)
smoking is similar in R and NR except a higher frequency of wheezing during the last 12 month (R: 12.5%, NR: 5.6%, p = 0.03). The level of carbon monoxide in expired air is higher in NR (17.6 ppm) that in R [...] and R (24.8 ppm) among current smokers (p < 0.01). The main reasons for refusal are lack of time (27.5%), lack of interest for medical study (22.6%), fear of health professionals (18.3%) or the existence
Impact of the warm summer 2015 on emergency hospital admissions in Switzerland (Publications)
warmest regions (Ticino [8.4%, 95% CI 5.1-11.7%] and the Lake Geneva region [4.8%, 95% CI 3.0-6.7%]) and among the elderly population aged > /=75 years (5.1%, 95% CI 3.7-6.5%). Increased EHA during days with
Elemental composition of particulate matter and the association with lung function (Publications)
copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc within PM smaller than 2.5 mum (PM2.5) and smaller than 10 mum (PM10) was estimated using land-use regression models. Associations between [...] differences in observed effect sizes between studies. METHODS:: We conducted a multicenter study in 5 European birth cohorts-BAMSE (Sweden), GINIplus and LISAplus (Germany), MAAS (United Kingdom), and PIAMA
The contribution of spatial analysis to understanding HIV/TB mortality in children: a structural equation modelling approach (Publications)
relayed on a conceptual framework. Results: Fifty-four of 6,692 children aged 1-5 years died of HIV/TB, from a total of 5,084 households. Maternal death had the greatest effect on child HIV/TB mortality [...] determinants and their spatial distribution in the rural Agincourt sub-district for children aged 1-5 years in 2004. Our secondary aim was to model how the associated factors were interrelated as either
<em>CHI3L1 </em>polymorphisms, cord blood YKL-40 levels and later asthma development (Publications)
and measured cord blood YKL-40 levels by ELISA in (n = 170) infants. Lung function was performed at 5 weeks and 6 years. Respiratory health during the first year of life was assessed weekly by telephone [...] SNP rs10399805 was significantly associated with asthma at 6 years. The odds ratio for asthma was 4.5 (95 % CI 1.59-12.94) per T-allele. This finding was unchanged when adjusting for cord blood YKL-40 levels [...] asthma. SNPs in CHI3L1 and cord blood YKL-40 were not associated with lung...
Risk factors for Buruli ulcer in Ghana - a case control study in the Suhum-Kraboa-Coaltar and Akuapem south districts of the eastern region (Publications)
of wetland in the neighborhood (OR = 3.9, 95% CI = 1.9-8.2), insect bites in water/mud (OR = 5.7, 95% CI = 2.5-13.1), use of adhesive when injured (OR = 2.7, 95% CI = 1.1-6.8), and washing in the Densu river [...] District) diagnosed according to the WHO clinical case definition for BU and matched with age- (+/-5 years), gender-, and community controls. A structured questionnaire on host, demographic, environmental
