Perception of cure among leprosy patients post completion of multi-drug therapy (Publications)
unhealed (OR 4.6; 95% CI 2.5-8.5). Patients with physical disabilities (PD) grade 1 and 2 at the time of the study had a 3.1 (OR 3.1; 95% CI 1.3-7.4) and 8.8 (OR 7.7; 95% CI 3.5-21.9) times higher likelihood
Aetiology of fever in returning travelers and migrants: a systematic review and meta-analysis (Publications)
ratios demonstrated that splenomegaly, thrombocytopenia and hyperbilirubinemia were respectively 5-14, 3-11 and 5-7 times more likely in malaria than non-malaria patients. High variability of results between [...] extraction. Tropical infections accounted for 33% of fever diagnoses, with malaria causing 22%, dengue 5% and enteric fever 2%. Non-tropical infections accounted for 36% of febrile cases, with acute gastr
Rabies control in Liberia: joint efforts towards zero by 30 (Publications)
an accurately costed mass dog vaccination strategy were developed. Liberia is currently at stage 1.5/5 of the Stepwise Approach towards Rabies Elimination (SARE) tool, which corresponds with countries that [...] local-level interventions (e.g. dog vaccination campaigns) to the national level. Overall an estimated 5.3 - 8 million USD invested over 13 years is needed to eliminate rabies in Liberia by 2030. Liberia still
Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents (Publications)
the most promising results (IC50 = 5.63 mug/mL to 18.71 mug/mL). Incidentally, NTD-B4-DCM and NTD-B2-DCM, also exhibited the greatest antitrypanosomal activities (IC50 = 5.63 mug/mL and 7.12 mug/mL, respectively) [...] from traditional medicines used to treat schistosomiasis, displayed the highest activity (IC50 = 30.5 mug/mL and 30.8 mug/mL, respectively) against Schistosoma mansoni adult worms. NTD-B2-DCM, also obtained
Constructing a malaria-related health service readiness index and assessing its association with child malaria mortality: an analysis of the Burkina... (Publications)
and malaria mortality in children under the age of 5 years in Burkina Faso. Methods: Data on inpatients visits and malaria-related deaths in under 5-year-old children were extracted from the national Health [...] Malaria mortality rate in medical centres was 4.8 times higher than that of peripheral health centres (3.5% vs. 0.7%, p < 0.0001). Essential medicines was the domain with the lowest readiness (only 0.1% of medical
Monitoring <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> using microsatellite markers indicates limited changes in population structure... (Publications)
markers. Despite parasite prevalence declining substantially (East Sepik Province: Pf=54.9-8.5%, Pv=35.7-5.6%, Madang Province: Pf=38.0-9.0%, Pv: 31.8-19.7%), genetically diverse and intermixing parasite [...] remained high throughout the study period (East Sepik: Rs =11.4-9.3, He =0.83-0.80; Madang: Rs =12.2-14.5, He =0.85-0.88). Although genetic differentiation values increased between provinces over time, no
<em>CHI3L1 </em>polymorphisms, cord blood YKL-40 levels and later asthma development (Publications)
and measured cord blood YKL-40 levels by ELISA in (n = 170) infants. Lung function was performed at 5 weeks and 6 years. Respiratory health during the first year of life was assessed weekly by telephone [...] SNP rs10399805 was significantly associated with asthma at 6 years. The odds ratio for asthma was 4.5 (95 % CI 1.59-12.94) per T-allele. This finding was unchanged when adjusting for cord blood YKL-40 levels [...] asthma. SNPs in CHI3L1 and cord blood YKL-40 were not associated with lung...
Prevalence of drug-resistance mutations and HIV-1 subtypes in a HIV-1 infected COHORT in rural Tanzania (Publications)
The prevalence of major DR-SNPs in 2005-2007 in the RT gene was determined: K103N (5.0%), Y181C (2.5%), M184V (2.5%), G190A (1.7%) and M41L, K65KR, K70KR and L74LV (0.8%). In samples from 2009 only K103N
Elemental composition of particulate matter and the association with lung function (Publications)
copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc within PM smaller than 2.5 mum (PM2.5) and smaller than 10 mum (PM10) was estimated using land-use regression models. Associations between [...] differences in observed effect sizes between studies. METHODS:: We conducted a multicenter study in 5 European birth cohorts-BAMSE (Sweden), GINIplus and LISAplus (Germany), MAAS (United Kingdom), and PIAMA
Risk factors for Buruli ulcer in Ghana - a case control study in the Suhum-Kraboa-Coaltar and Akuapem south districts of the eastern region (Publications)
of wetland in the neighborhood (OR = 3.9, 95% CI = 1.9-8.2), insect bites in water/mud (OR = 5.7, 95% CI = 2.5-13.1), use of adhesive when injured (OR = 2.7, 95% CI = 1.1-6.8), and washing in the Densu river [...] District) diagnosed according to the WHO clinical case definition for BU and matched with age- (+/-5 years), gender-, and community controls. A structured questionnaire on host, demographic, environmental