ExpoApp: an integrated system to assess multiple personal environmental exposures (Publications)
level between ExpoApp and reference tools was 86.6% (86.5-86.7) and 75.7% (71.5-79.4), respectively. ExpoApp estimated that participants inhaled 16.5x10(10) particles/day of UFP and had almost no contact
Antagonistic effects of <em>Plasmodium</em>-helminth co-infections on malaria pathology in different population groups in Côte d'Ivoire (Publications)
participants aged 5-16 years from a school-based study. CONCLUSIONS/SIGNIFICANCE: No exacerbation from co-infection with Plasmodium and helminths was observed, neither in participants aged 5-18 years nor in [...] of antagonistic nature but varied in magnitude and species combination. In study participants aged 5-18 years from community-based studies, Plasmodium-hookworm co-infection showed an antagonistic interaction
Incidence, remission and mortality of convulsive epilepsy in rural Northeast South Africa (Publications)
mortality ratio was 2.6 (95%CI: 1.7-3.5), with 33.3% of deaths directly related to epilepsy. Mortality was higher in men than women (adjusted rate ratio (aRR) 2.6 (95%CI: 1.2-5.4)), and was significantly associated [...] associated with older ages (50+ years versus those 0-5 years old (RR 4.8 (95%CI: 0.6-36.4)). CONCLUSIONS: The crude incidence was lower whilst mortality rates were similar to other African studies; however
Estimating the global burden of endemic canine rabies (Publications)
prophylaxis (PEP, 20%) and lost income whilst seeking PEP (15.5%), with only limited costs to the veterinary sector due to dog vaccination (1.5%), and additional costs to communities from livestock losses [...] CIs: 1.6-10.4 million) disability-adjusted life years (DALYs) and 8.6 billion USD (95% CIs: 2.9-21.5 billion) economic losses annually. The largest component of the economic burden is due to premature
Monitoring <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> using microsatellite markers indicates limited changes in population structure... (Publications)
markers. Despite parasite prevalence declining substantially (East Sepik Province: Pf=54.9-8.5%, Pv=35.7-5.6%, Madang Province: Pf=38.0-9.0%, Pv: 31.8-19.7%), genetically diverse and intermixing parasite [...] remained high throughout the study period (East Sepik: Rs =11.4-9.3, He =0.83-0.80; Madang: Rs =12.2-14.5, He =0.85-0.88). Although genetic differentiation values increased between provinces over time, no
Aetiology of fever in returning travelers and migrants: a systematic review and meta-analysis (Publications)
ratios demonstrated that splenomegaly, thrombocytopenia and hyperbilirubinemia were respectively 5-14, 3-11 and 5-7 times more likely in malaria than non-malaria patients. High variability of results between [...] extraction. Tropical infections accounted for 33% of fever diagnoses, with malaria causing 22%, dengue 5% and enteric fever 2%. Non-tropical infections accounted for 36% of febrile cases, with acute gastr
Rabies control in Liberia: joint efforts towards zero by 30 (Publications)
an accurately costed mass dog vaccination strategy were developed. Liberia is currently at stage 1.5/5 of the Stepwise Approach towards Rabies Elimination (SARE) tool, which corresponds with countries that [...] local-level interventions (e.g. dog vaccination campaigns) to the national level. Overall an estimated 5.3 - 8 million USD invested over 13 years is needed to eliminate rabies in Liberia by 2030. Liberia still
Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents (Publications)
the most promising results (IC50 = 5.63 mug/mL to 18.71 mug/mL). Incidentally, NTD-B4-DCM and NTD-B2-DCM, also exhibited the greatest antitrypanosomal activities (IC50 = 5.63 mug/mL and 7.12 mug/mL, respectively) [...] from traditional medicines used to treat schistosomiasis, displayed the highest activity (IC50 = 30.5 mug/mL and 30.8 mug/mL, respectively) against Schistosoma mansoni adult worms. NTD-B2-DCM, also obtained
Constructing a malaria-related health service readiness index and assessing its association with child malaria mortality: an analysis of the Burkina... (Publications)
and malaria mortality in children under the age of 5 years in Burkina Faso. Methods: Data on inpatients visits and malaria-related deaths in under 5-year-old children were extracted from the national Health [...] Malaria mortality rate in medical centres was 4.8 times higher than that of peripheral health centres (3.5% vs. 0.7%, p < 0.0001). Essential medicines was the domain with the lowest readiness (only 0.1% of medical
Malaria infection prevalence and sensitivity of reactive case detection in Zanzibar (Publications)
households and 0.4% of those residing in non-index households tested positive (OR = 8.4; 95%CI: 5.7, 12.5). Of 6,281 participants tested by quantitative polymerase chain reaction (qPCR), 8.4% of those residing [...] within 50 m of the index household as compared with those located farther away (OR = 0.8, 95%CI: 0.5, 1.4). Sensitivity of RDT to detect qPCR-detectable infections was 34% (95%CI: 26.4, 42.3). CONCLUSIONS: