Identification of oleamide in <em>Guatteria</em> recurvisepala by LC/MS-Based <em>Plasmodium falciparum</em> thioredoxin reductase ligand binding... (Publications)
20-min gradient of 95 % B consisting of (A) 0.1 % formic acid in 95 % H (2)O-5 % ACN, and (B) 0.1 % formic acid in 95 % ACN-5% H (2)O in an LC-QTOF-MS. Tandem MS of the protonated molecule M/Z 282.2792 [...] ligand identified in the extract of GUATTERIA RECURVISEPALA displayed a relative binding affinity of 3.5-fold when incubated with 1 microM PFTrxR. The ligand corresponding to the protonated molecule M/Z 282
Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women (Publications)
cough with phlegm and mild COPD was estimated at 21.4% and 39.5%, respectively, if no air pollution reduction was assumed, and at 13.3% and 17.5%, respectively, if air pollution reduction was assumed. CONCLUSION: [...] chronic cough with phlegm production and mild COPD at baseline investigation compared to follow-up was 9.5% vs. 13.3% and 8.6% vs. 18.2%, respectively. A steeper decline of PM10 was observed in the industrialized
Effect of immediate initiation of antiretroviral treatment on the risk of acquired HIV drug resistance (Publications)
acquired drug resistance was 3.2% (2.8,3.5) for immediate initiation, 3.1% (2.7,3.3) for initiation with CD4 cell count less than 500 cells/mul, and 2.8% (2.5,3.0) for initiation with CD4 cell count less [...] restricted to individuals with baseline in 2005-2015, the corresponding estimates were 1.9% (1.8, 2.5), 1.9% (1.7, 2.4), and 1.8% (1.7, 2.2). CONCLUSION: Our findings suggest that the risk of acquired drug
Risk factors for the carriage of<em> Streptococcus infantarius </em>subspecies <em>infantarius </em>isolated from African fermented dairy products (Publications)
prevalence of SBSEC and Sii carriage was 23.2% (confidence interval CI 95% = 18.9-27.5) and 12.0% (CI 95% = 8.4-15.5) for stool, respectively. Prevalence of Sii was significantly higher in consumers of [...] as in persons handling livestock (OR = 3.9; 95% CI = 1.6-9.3) and livestock primary products (OR = 5.7; 95% CI = 2.3-14.3). The closer contact with livestock was a risk factor for Sii fecal carriage. Sii
Effect and cost of two successive home visits to increase HIV testing coverage: a prospective study in Lesotho, Southern Africa (Publications)
respectively (p < 0.001) and acceptance for testing was 88.5% in rural and 79.5% in urban areas (p < 0.001), resulting in a coverage of 61.8 and 61.5%, respectively. After catch-up visit, the HTC coverage
Spatio-temporal modelling of changes in air pollution exposure associated to the COVID-19 lockdown measures across Europe (Publications)
measures taken to tackle the virus in Europe reduced the average surface concentrations of NO2 and PM2.5 by 29.5% (95% Bayesian credible interval: 28.1%, 30.9%) and 25.9% (23.6%, 28.1%), respectively. To our knowledge [...] (BST) models that assess changes in the surface nitrogen dioxide (NO2) and fine particulate matter (PM2.5) concentration across the continent. We fitted BST models to measurements of the two pollutants in 2020
Association between household solid fuel use and tuberculosis: cross-sectional data from the Mongolian national tuberculosis prevalence survey (Publications)
ratio (aOR): 1.5; 95% confidence interval (CI): 1.1-2.1), male gender (aOR: 2.2; 95% CI: 1.6-3.2), divorced or widowed (aOR: 2.6; 95% CI: 1.7-3.8), daily smoker (aOR: 1.8; 95% CI: 1.3-2.5), contact with [...] with an active TB case (aOR: 1.7; 95% CI: 1.2-2.3), being underweight (aOR: 3.7; 95% CI: 2.4-5.7), and previous history of TB (aOR: 4.3; 95% CI: 3.0-6.1) were significantly associated with bacteriologically
Exposure to surrounding greenness and natural-cause and cause-specific mortality in the ELAPSE pooled cohort (Publications)
associations between greenness exposure and mortality after adjusting for fine particulate matter (PM2.5), nitrogen dioxide (NO2) and road traffic noise. RESULTS: The pooled study population comprised 327 [...] In the main fully adjusted model, 0.1 unit increment of NDVI inside 300-m grid was associated with 5% lower risk of natural-cause mortality (Hazard Ratio (HR) 0.95 (95% CI: 0.94, 0.96)). The associations [...] associations attenuated after adjustment for air pollution [HR (95% CI): 0.97...
Parental and provider vaccine hesitancy and non-timely childhood vaccination in Switzerland (Publications)
Vaccines (PACV) 5-item survey instrument to 1256 parents and their children's pediatricians (N = 112, 40 CM-oriented, 72 biomedical [not CM-oriented]) to identify moderately (PACV-score 5-6) and highly [...] hesitant CM providers had 3.3 higher odds of non-timely vaccination for the 1st dose of measles and 3.5 higher odds for 1st dose of polio/pertussis/tetanus. CONCLUSION: VH by both parents and providers each
Effect of lifting COVID-19 restrictions on utilisation of primary care services in Nepal: a difference-in-differences analysis (Publications)
s was associated with an average increase per palika of 57.5 contraceptive users (95% CI 14.6 to 100.5), 15.6 antenatal care visits (95% CI 5.3 to 25.9) and 1.6 child pneumonia visits (95% CI 0.2 to 2