Skin wounds in a rural setting of Côte d'Ivoire: population-based assessment of the burden and clinical epidemiology (Publications)
furuncles (5.1%), burns (2.9%) and Buruli ulcer (2.2%). Most wounds were acute and smaller than 5 cm2 in size. 22.0% (176/799) of wounds showed evidence of secondary bacterial infection. 35.5% (22/62) of
Multi-dose priming regimens of PfSPZ vaccine: safety and efficacy against controlled human malaria infection in Equatoguinean adults (Publications)
at 4 or 16 weeks (9 x 105 PfSPZ/dose). The regimens were G1: days 1, 3, 5, 7, and 113; G2: days 1, 3, 5, and 7; G3: days 1, 3, 5, 7, and 29; and G4: days 1, 8, and 29). All doses were 9 x 105 PfSPZ. T
Characterising co-infections with <em>Plasmodium </em>spp., <em>Mansonella perstans</em> or <em>Loa loa </em>in asymptomatic children, adults and... (Publications)
screened. Positivity rates of M. perstans and L. loa were 6.6% and 1.5%, respectively. M. perstans infection were more prominent in male (10.5%) compared to female (3.9%) survey participants. M. perstans parasite [...] influenced the infection rate with people belonging to the lowest socio-economic quintile more than 3 and 5 times more likely to be L. loa and M. perstans infected, respectively. No increased risk of being c
Prevalence and predictors of residual antibiotics in children's blood in community settings in Tanzania (Publications)
detected antibiotics were trimethoprim (144/1699; 8.5%), sulfamethoxazole (102/1699; 6.0%), metronidazole (61/1699; 3.6%) and amoxicillin (43/1699; 2.5%). The strongest predictors of residual antibiotics [...] home (aOR=2.9; 95% CI: 2.0-4.1) and reported consumption of antibiotics in the last two weeks (aOR=2.5; 95% CI: 1.6-3.9). However, half (145/296) of the children who had residual antibiotics in their blood
Seasonal malaria chemoprevention and the spread of <em>Plasmodium falciparum </em>quintuple-mutant parasites resistant to sulfadoxine-pyrimethamine: a... (Publications)
monthly cycles to children aged 3 months to 5 years (with 95% initial coverage declining each cycle), the quintuple mutant required 53·1 years (95% CI 50·5-56·0) to spread from 1% to 50% of inoculations [...] yrimethamine plus amodiaquine prevents millions of clinical malaria cases in children younger than 5 years in Africa's Sahel region. However, Plasmodium falciparum parasites partially resistant to sul
Comparison of NO2 and BC predictions estimated using Google Street View-based and conventional European-wide LUR models in Copenhagen, Denmark (Publications)
segments and 0.40 at the residential level. The ratio of percentile 97.5 to 2.5 for NO2 across the study area streets using Google-MM NO2 was 4.5, while using EUW-LUR, this was 2.1. These NO2 ratios at residences
Effect of ambient air pollution on hospital admission for respiratory diseases in Hanoi children during 2007-2019 (Publications)
of hospital admissions per 10 μg/m(3) increase in daily average particulate matter (e.g. PM(1), PM(2.5), PM(10)), Sulfur Dioxide (SO(2)), Nitrogen Dioxide (NO(2)), 8-h maximum Ozone and per 1000 μg/m(3) [...] Hanoi by using the coefficient at lag 0. A 10 μg/m(3) increase in the concentration of PM(10), PM(2.5), PM(1), SO(2), NO(2), O(3) 8-h maximum and 1000 μg/m(3) increase in CO concentration was associated [...] upper respiratory diseases are related to increments in NO(2) and CO. For...
Malaria vectors and their blood-meal sources in an area of high bed net ownership in the western Kenya highlands (Publications)
sensu stricto obtained blood-meals from humans, 26.5 % from goats and 18.4 % from bovines. Single blood-meal sources by An. gambiae s.s. from humans were 26.5 %, 8.2 % from bovines and 2.0 % from goats. Mixed [...] Mixed blood-meal sources by An. gambiae s.s. identified included: 24.5 % human/goat, 10.2 % human/bovine, 8.2 % human/bovine/goat and also 8.2 % bovine/goat. One An. arabiensis mosquito obtained blood-meal
Insights into the genetic diversity of <em>Mycobacterium tuberculosis</em> in Tanzania (Publications)
Lineage 4 was the most frequent (n = 866, 42.5%), followed by Lineage 3 (n = 681, 33.4%) and 1 (n = 336, 16.5%), with Lineage 2 being the least frequent (n = 92, 4.5%). We found Lineage 2 to be independently
Sonography to rule out tuberculosis in sub-Saharan Africa: a prospective observational study (Publications)
= 2.48; 95% CI, 1.52-5.03; P = .001 per degrees C increase) remained associated with tuberculosis. A combination of > /=1 FASH sign, abnormal chest x-ray, and temperature > /=37.5 degrees C had 99.1% [...] analyzed patients with a 6-month follow-up, 52.4% tested positive for human immunodeficiency virus, 21.5% had clinically suspected pulmonary tuberculosis, 3.7% had extrapulmonary tuberculosis, and 74.9% had