A population-based study on the implementation of treatment recommendations for chemotherapy in early breast cancer (Publications)
receptor (ER) status (OR, 3.8; 95% CI, 2.6-5.5), human epidermal growth factor receptor 2 (HER2) status (OR, 1.9; 95% CI, 1.3-2.7), and patient age (OR, 4.6; 95% CI, 3.5-6.2) were less important predictors for
Is misoprostol a safe, effective and acceptable alternative to manual vacuum aspiration for postabortion care? Results from a randomised trial in... (Publications)
desire to choose that method again (misoprostol = 94.5%, MVA = 86.6%; RR = 1.09 [95% CI 1.03-1.16]) and to recommend it to a friend (misoprostol = 94.5%, MVA = 85.2%; RR = 1.11 [95% CI 1.04-1.18]). CONCLUSION: [...] of treatment assigned, nearly all participants had a complete uterine evacuation (misoprostol = 94.5%, MVA = 99.1%; relative risk [RR] = 0.95 [95% CI 0.92-0.99]). Acceptability and satisfaction ratings
Identification of oleamide in <em>Guatteria</em> recurvisepala by LC/MS-Based <em>Plasmodium falciparum</em> thioredoxin reductase ligand binding... (Publications)
20-min gradient of 95 % B consisting of (A) 0.1 % formic acid in 95 % H (2)O-5 % ACN, and (B) 0.1 % formic acid in 95 % ACN-5% H (2)O in an LC-QTOF-MS. Tandem MS of the protonated molecule M/Z 282.2792 [...] ligand identified in the extract of GUATTERIA RECURVISEPALA displayed a relative binding affinity of 3.5-fold when incubated with 1 microM PFTrxR. The ligand corresponding to the protonated molecule M/Z 282
Effect of immediate initiation of antiretroviral treatment on the risk of acquired HIV drug resistance (Publications)
acquired drug resistance was 3.2% (2.8,3.5) for immediate initiation, 3.1% (2.7,3.3) for initiation with CD4 cell count less than 500 cells/mul, and 2.8% (2.5,3.0) for initiation with CD4 cell count less [...] restricted to individuals with baseline in 2005-2015, the corresponding estimates were 1.9% (1.8, 2.5), 1.9% (1.7, 2.4), and 1.8% (1.7, 2.2). CONCLUSION: Our findings suggest that the risk of acquired drug
Insights into the genetic diversity of <em>Mycobacterium tuberculosis</em> in Tanzania (Publications)
Lineage 4 was the most frequent (n = 866, 42.5%), followed by Lineage 3 (n = 681, 33.4%) and 1 (n = 336, 16.5%), with Lineage 2 being the least frequent (n = 92, 4.5%). We found Lineage 2 to be independently
Risk factors for the carriage of<em> Streptococcus infantarius </em>subspecies <em>infantarius </em>isolated from African fermented dairy products (Publications)
prevalence of SBSEC and Sii carriage was 23.2% (confidence interval CI 95% = 18.9-27.5) and 12.0% (CI 95% = 8.4-15.5) for stool, respectively. Prevalence of Sii was significantly higher in consumers of [...] as in persons handling livestock (OR = 3.9; 95% CI = 1.6-9.3) and livestock primary products (OR = 5.7; 95% CI = 2.3-14.3). The closer contact with livestock was a risk factor for Sii fecal carriage. Sii
Comparison of NO2 and BC predictions estimated using Google Street View-based and conventional European-wide LUR models in Copenhagen, Denmark (Publications)
segments and 0.40 at the residential level. The ratio of percentile 97.5 to 2.5 for NO2 across the study area streets using Google-MM NO2 was 4.5, while using EUW-LUR, this was 2.1. These NO2 ratios at residences
Effect of ambient air pollution on hospital admission for respiratory diseases in Hanoi children during 2007-2019 (Publications)
of hospital admissions per 10 μg/m(3) increase in daily average particulate matter (e.g. PM(1), PM(2.5), PM(10)), Sulfur Dioxide (SO(2)), Nitrogen Dioxide (NO(2)), 8-h maximum Ozone and per 1000 μg/m(3) [...] Hanoi by using the coefficient at lag 0. A 10 μg/m(3) increase in the concentration of PM(10), PM(2.5), PM(1), SO(2), NO(2), O(3) 8-h maximum and 1000 μg/m(3) increase in CO concentration was associated [...] upper respiratory diseases are related to increments in NO(2) and CO. For...
Sonography to rule out tuberculosis in sub-Saharan Africa: a prospective observational study (Publications)
= 2.48; 95% CI, 1.52-5.03; P = .001 per degrees C increase) remained associated with tuberculosis. A combination of > /=1 FASH sign, abnormal chest x-ray, and temperature > /=37.5 degrees C had 99.1% [...] analyzed patients with a 6-month follow-up, 52.4% tested positive for human immunodeficiency virus, 21.5% had clinically suspected pulmonary tuberculosis, 3.7% had extrapulmonary tuberculosis, and 74.9% had
Prevalence and predictors of residual antibiotics in children's blood in community settings in Tanzania (Publications)
detected antibiotics were trimethoprim (144/1699; 8.5%), sulfamethoxazole (102/1699; 6.0%), metronidazole (61/1699; 3.6%) and amoxicillin (43/1699; 2.5%). The strongest predictors of residual antibiotics [...] home (aOR=2.9; 95% CI: 2.0-4.1) and reported consumption of antibiotics in the last two weeks (aOR=2.5; 95% CI: 1.6-3.9). However, half (145/296) of the children who had residual antibiotics in their blood