Rapid and non-destructive detection and identification of two strains of <em>Wolbachia</em> in <em>Aedes aegypti</em> by near-infrared spectroscopy (Publications)
males infected with wMelPop from uninfected wild type samples with an accuracy of 96% (N = 299) and 87.5% (N = 377), respectively. Similarly, females and males infected with wMel were differentiated from [...] and wMel transinfected females with an accuracy of 96.6% (N = 442) and males with an accuracy of 84.5% (N = 443). This non-destructive technique is faster than the standard polymerase chain reaction diagnostic
Challenges associated with management of Buruli ulcer/human immunodeficiency virus coinfection in a treatment center in Ghana: a case series study (Publications)
alone (2.5%; 279/11,125; P = 0.001). All seven BU/HIV-coinfected cases enrolled in the study presented with very large (category III) lesions with four having multiple lesions compared with 54.5% of category
Whole genome sequencing and spatial analysis identifies recent tuberculosis transmission hotspots in Ghana (Publications)
and ArcGIS. Of the 452 traditional genotype clustered genomes, 314 (69.5%) were confirmed clusters with a median cluster size of 7.5 genomes and an interquartile range of 4-12. Recent tuberculosis (TB)
Do instructional videos on sputum submission result in increased tuberculosis case detection? A randomized controlled trial (Publications)
39.1 years (interquartile range 37.0-50.0); 94 (47%) were females, 106 (53%) were males, and 49 (24.5%) were HIV-infected. We found that the instructional video intervention was associated with detection [...] CI] 45.7-65.9%, sputum smear positive patients in the intervention group versus 23%, 95% CI 15.2-32.5%, in the control group, p /=3ml (78%, 95% CI 68.6-85.7%, versus 45%, 95% CI 35.0-55.3%, p
Orally active antischistosomal early leads identified from the open access malaria box (Publications)
compounds were investigated in vivo. PRINCIPAL FINDINGS: Promising antischistosomal activity (IC50: 1.4-9.5 microM) was observed for 34 compounds against schistosomula. Three compounds presented IC50 values between [...] with a single oral 400 mg/kg dose of these drugs resulted in significant worm burden reductions of 52.5% and 40.8%, respectively. CONCLUSIONS/SIGNIFICANCE: The two candidates identified by investigating the
An intra-COVID-19 assessment of hand hygiene facility, policy and staff compliance in two hospitals in Sierra Leone: is there a difference between... (Publications)
capital city (17.0%) hospitals. The HH levels for the capital city and regional hospitals were 277.5 and 262.5 respectively. Despite the COVID-19 pandemic, there are still challenges with HH compliance in Sierra
Physical activity and sedentary behavior among schoolchildren: a 34-country comparison (Publications)
compare levels of physical activity and sedentary behavior in schoolchildren from 34 countries across 5 WHO Regions. STUDY DESIGN: The analysis included 72,845 schoolchildren from 34 countries that participated [...] ons, with the lowest prevalence in Philippines and Zambia (both 8.8%) and the highest in India (37.5%). The prevalence of walking or riding a bicycle to school ranged from 18.6% in United Arab Emirates
Isolation and structural elucidation of compounds from <em>Pleiocarpa bicarpellata</em> and their <em>in vitro</em> antiprotozoal activity (Publications)
falciparum (IC50 value of 3.5 microg/mL). Among the compounds isolated, tubotaiwine (13) displayed the most significant antiplasmodial activity with an IC50 value of 8.5 microM and a selectivity index
Associations between particulate matter composition and childhood blood pressure - the PIAMA study (Publications)
potassium, nickel, sulfur, silicon, vanadium, and zinc in particles with diameters of less than 2.5µm (PM2.5) and 10µm (PM10) were estimated by land-use regression modeling for the home addresses of the
Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019 (Publications)
effects of medical treatment. From 1990 to 2019, global mortality rates declined by 34.4% (from 17.5 to 11.5 per 100 000) for transport injuries, and by 47.7% (from 15.9 to 8.3 per 100 000) for unintentional [...] nal injuries. However, in low-SDI nations the absolute number of deaths increased (by 80.5% to 42 774 for transport injuries and by 39.4% to 31 961 for unintentional injuries). In the high-SDI quintile [...] 838 in 2010 to 699 in 2019. This was a substantially slower pace of reduction...
