Measuring in-cabin school bus tailpipe and crankcase PM2.5: a new dual tracer method (Publications)
and applied to two school buses in Seattle in 2005 to quantify in-cabin fine particulate matter (PM2.5) concentrations attributable to the buses' diesel engine tailpipe (DPMtp) and crankcase vent (PMck) [...] and 1.3 microg/m3, respectively). For comparison, average closed- and open-window in-cabin total PM2.5 concentrations were 26 and 12 microg/m3, respectively. Despite the relatively short in-cabin sampling
Source apportionment of population representative samples of PM2.5 in three European cities using structural equation modelling (Publications)
and efficient reduction of the substantial public health risks associated with fine particles (PM(2.5)). Traffic is an important source combustion particles, but also a significant source of resuspended [...] such studies are therefore poorly representative of the actual exposures. The current study uses PM(2.5) data observed at population based random sampled residential locations in Athens, Basle and Helsinki [...] variability of elemental (R(2)> 0.6 except for Ca in Basle 0.38) and chemical...
Epidemiology and clinical features of imported dengue fever in Europe: sentinel surveillance data from TropNetEurop5 (Publications)
Travelers have the potential both to acquire and to spread dengue virus infection. The incidence of dengue fever (DF) among European travelers certainly is underestimated, because few centers use stan
Anaerobic performance in 5- to 7-yr-old children of low birthweight (Publications)
PURPOSE: This study was intended to determine whether anaerobic muscle performance is deficient in 5- to 7-yr-old children of extremely low birthweight (ELBW, 500-999 g) and very low birthweight (VLBW
PM2.5 and NO2 assessment in 21 European study centres of ECRHS II: annual means and seasonal differences (Publications)
health, in particular asthma and change of pulmonary function. Since PM2.5 is not routinely monitored in Europe, we measured PM2.5 concentrations in 21 participating centres to estimate 'background' exposure [...] values of PM2.5 were determined from measuring periods between June 2000 and November 2001. Sampling was conducted for 7 days per month for a year. Annual and winter mean concentrations of PM2.5 vary substantially [...] The range of PM2.5 mass concentrations obtained in ECRHS II is...
Examining the representativeness of home outdoor PM2.5, EC, and OC estimates for daily personal exposures in southern California (Publications)
diameter less than 2.5 ?m (PM(2.5)), elemental carbon (EC), and organic carbon (OC) during sixteen 10-day monitoring runs. Regression models to predict daily home outdoor PM(2.5), EC, and OC were constructed [...] variance explained (R(2)) was 0.97 and 0.94 for PM(2.5), 0.91 and 0.83 for OC, and 0.76 and 0.87 for EC in Riverside and Whittier, respectively. The PM(2.5) outdoor estimates correlated well with the personal [...] other pollutants. While home outdoor estimates provide good...
Evaluation of a sampling strategy for estimation of long-term PM2.5 exposure for epidemiological studies (Publications)
As part of the European Community Respiratory Health Survey (ECRHS) PM2.5 (particles collected with an upper 50% cut point of 2.5 microm aerodynamic diameter) was measured using an EPA-WINS (Environmental [...] the 'true' long-term averages, which were estimated using all available daily means. The daily PM2.5 means, obtained by both instruments operated in parallel, were only slightly different (the mean difference
The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone (Publications)
An unsaturated dispiro 1,2,4,5-tetraoxane formed by peroxidation of (+)-dihydrocarvone was converted into four structurally diverse derivatives. X-ray crystallographic analysis shows that the structures [...] structures possess central tetraoxane rings with spiro-2,5-disubstituted cyclohexylidene substituents and 6-membered rings in classical chair conformations. As polarity in the tetraoxane series increased, in vitro
Structure-activity relationship studies of orally active antimalarial 3,5-substituted 2-aminopyridines (Publications)
potential cardiotoxicity liabilities identified with earlier frontrunner compounds, a number of new 3,5-diaryl-2-aminopyridine derivatives were synthesized. Several compounds exhibited potent antiplasmodial
