Inhibition of <em>Leishmania donovani</em> transformation by hamster spleen homogenates and active human lymphocytes (Publications)
from one stage to the next includes morphological antigenic, physiological, and infectivity changes2–5.
Ultrastructural changes in midgut cells of female <em>Aedes aegypti</em> L. (Insecta, Diptera) after starvation or sugar diet (Publications)
posterior part of the midgut in female Aedes aegypti was partly changed after starvation periods of 5 or 8 days. Most obvious is a drastic reduction of the amount of rough endoplasmic reticulum (rer), which
Ultrastructural changes in midgut cells of female <em>Aedes aegypti</em> L. (Insecta, Diptera) after starvation or sugar diet (Publications)
posterior part of the midgut in female Aedes aegypti was partly changed after starvation periods of 5 or 8 days. Most obvious is a drastic reduction of the amount of rough endoplasmic reticulum (rer), which
VErtical GrAdient Study (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/vertical-gradient-study
knowledge for four key air pollutants, both in real-time (Particle Number Concentration (PNC), PM2.5 and black carbon) and on the long-term (NO2), and has two components: 1) A real-time (short-term) component [...] which aims to characterize vertical gradients at 10 locations in Basel for 3 air pollutants (PNC, PM2.5 and black carbon) using quality real-time instruments which are sampling simultaneously at 6 different
TNFA-308 in Two International Population-Based Cohorts Shows Increased Risk for Asthma (Publications)
polymorphism was associated with increased asthma prevalence (odds ratio for the A allele=1.3, 95%CI 1.1-1.5) and with bronchial hyper-responsiveness (OR=1.2, 95%CI 1.0-1.3). No consistent association was found [...] meta-analysis of 17 studies showed an increased asthma risk of the TNFA-308 A allele (OR=1.3, 95%CI 1.2-1.5).The TNFA-308 polymorphism is associated with a moderately increased risk for asthma and bronchial
The value of [18F]FDG-PET in the diagnosis of large-vessel vasculitis and the assessment of activity and extent of disease (Publications)
assessment of activity and extent of disease. METHODS: Twenty-six consecutive patients (21 females, 5 males; median age - years, range 17-86 years) with giant cell arteritis or Takayasu's arteritis were [...] Follow-up scans were performed in four patients. Twenty-six age- and gender-matched controls (21 females, 5 males; median age 71 years, range 17-86 years) were included. The severity of large-vessel [(18)F]FDG
Use and misuse of a discount voucher scheme as a subsidy for insecticide-treated nets for malaria control in southern Tanzania (Publications)
been used in two rural districts of southern Tanzania as a way to target subsidies to children under 5 years and pregnant women. We assessed appropriate use and misuse of discount vouchers through a follow-up [...] Moreover, 94% of the ITNs bought with vouchers were used by those intended, women and children under 5 years. However, up to 48% (50/104) of the vouchers had been misused at the clinics that issued them
Allergic disease and atopic sensitization in children in relation to measles vaccination and measles infection (Publications)
Anthroposophic Lifestyle study, conducted in 5 European countries (Austria, Germany, the Netherlands, Sweden, and Switzerland). The children were between 5 and 13 years of age and represented farm children
Pharmacokinetics, <em>Trypanosoma brucei gambiense</em> efficacy and time of drug action of DB829, a preclinical candidate for treatment of second... (Publications)
against the T. b. rhodesiense STIB900 strain. A single dose of DB829 administered intraperitoneally (5 mg/kg) cured all mice infected with different T. b. gambiense strains. No cross-resistance was observed [...] dose of DB829 (20 mg/kg) administered intraperitoneally clears parasites from mouse blood within 2-5 days. In summary, DB829 is a promising preclinical candidate for the treatment of first and second stage
Synthesis and antimalarial testing of neocryptolepine analogues: addition of ester function in SAR study of 2,11-disubstituted indolo[2,3-b]quinolines (Publications)
synthesis, and in vitro and in vivo antimalarial evaluations of certain ester-modified neocryptolepine (5-methyl-5H-indolo[2,3-b]quinoline) derivatives. The modifications were carried out by introducing ester groups