Prevalence and determinants of undernutrition in schoolchildren in the Kilombero district, South-Eastern Tanzania (Publications)
underweight, overweight, and obesity was 11.8%, 4.3%, 3.9%, 11.1%, and 2.0%, respectively. Overall, 1.5% of the children had malaria, as determined by rapid diagnostic tests, and 0.4% had severe anaemia. [...] emphasise the need for school-based health and nutrition programmes targeting children beyond the age of 5 to improve their nutritional status and mitigate potential adverse effects on health, cognition, and
Substance use referral, treatment utilization, and patient costs associated with problematic substance use in people living with HIV in Cape Town,... (Publications)
treatment program. Only 1.5% of the enrolled patient study sample (N = 66) reported lifetime referral to SU treatment. On average, patients with untreated SU spent 33.3% (SD=34.5%) of their monthly household
Digital tools to improve parenting behaviour in low-income settings: a mixed-methods feasibility study (Publications)
y cost-effective means for providing early child development services in low-income settings. This 5-month mixed-methods pilot study evaluated the feasibility of using Afinidata, a comprehensive Facebook [...] reported using the platform at least once, and of those, 87% rated it as useful to very useful. After 5 months, 42% of mothers were still active on the platform, with little variation between urban and rural
Whole genome sequencing for drug resistance profile prediction in<em> Mycobacterium tuberculosis</em> (Publications)
73-99 % of cases, depending on the drug. Our data suggests that the established critical concentration (5 mg/L) for ethambutol resistance (MGIT 960 system) is too high and may misclassify strains as susceptible [...] resistance mechanisms. The overall sensitivity and specificity of whole genome-based DST were 86.8 % and 94.5 %, respectively.Despite some limitations, whole genome sequencing has the potential to infer resistance
Impact of adolescents' screen time and nocturnal mobile phone-related awakenings on sleep and general health symptoms: a prospective cohort study (Publications)
their own mobile phone per month were more likely to have developed restless sleep (Odds Ratio (OR): 5.66, 95% Confidence Interval: 2.24(-)14.26) and problems falling asleep (3.51, 1.05(-)11.74) within one [...] ty (1.76, 1.02(-)3.03), lack of energy (1.76, 1.04(-)2.96) and lack of concentration (2.90, 1.55(-)5.42). Our results suggest a detrimental effect of screen time and mobile phone-related awakenings on
Dental care behaviour in Switzerland (Publications)
including caries/filling/endodontic treatment (10%), crowns/FDP/RDP/implants (8%), toothache (5%), extraction (5%), periodontal complaints (2%), or orthodontic appliances (2%) were more heterogeneously d
Development and validation of an enantioselective LM-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in... (Publications)
and concentrated on a C-18 trapping column. The analytical range for each PZQ enantiomer was 0.01-2.5µg/mL, and 0.1-25µg/mL for the metabolite. The method met the requirements regarding precision (±15% [...] pharmacokinetic studies. Moreover, the enantioselective separation was achieved with a run time of 11.5min and a simple sample processing method.
Use of B-type natriuretic peptide for the management of women with dyspnea (Publications)
treatment was $4,781 in the BNP group (95% confidence interval 3,854 to 5,708) versus $6,843 in the control group (95% confidence interval 5,611 to 8,074, p = 0.009). In-hospital mortality rates were 4% in the
Environmental tobacco smoke exposure and diabetes in adult never-smokers (Publications)
participants' study area as a random effect. RESULTS: The prevalence of DM and ETS in the sample was 5.5% and 47% respectively. There were 2779 never-smokers with 4% diabetes prevalence. Exposure to ETS increased
Demand-side financing in the form of baby packages in Northern Mozambique: results from an observational study (Publications)
in rural Africa. The objective was to test the impact on Institutional Birth Rates of giving a USD 5.50 baby package incentive to every woman who came to give birth in a health centre in a rural, poor [...] 15 districts serving as controls. The total population in the 16 districts in 2006 was just under 1.5 million people. IBRs were observed from 2006 to 2013 (53 months before and 55 months after the intervention