Epidemiology of community-onset bloodstream infections in Bouaké, central Côte d'Ivoire (Publications)
Côte d'Ivoire, to determine the aetiology of community-onset BSI. The prevalence of bacteraemia was 22.5%, with children being most commonly affected. Enterobacteriaceae (predominantly Klebsiella pneumoniae
Characterization of di-, tri-, and tetranucleotide microsatellite markers with perfect repeats for<em> Trypanosoma brucei</em> and related species (Publications)
tri-, and tetranucleotide microsatellite loci with perfect repeats (only one motif) exhibiting between 5 and 16 alleles in T. brucei isolates from all over Africa and from all described subspecies. The mi
Vaccines for enteric diseases: update on recent developments (Publications)
The 5th International Conference on Vaccines for Enteric Diseases (VED) attracted more than 250 delegates, mainly from industrialized countries. A total of 56 papers were presented and 46 posters were
Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan... (Publications)
against malaria. We now present in-depth safety results from this study. 8922 children (enrolled at 5-17 months) and 6537 infants (enrolled at 6-12 weeks) were 1:1:1-randomized to receive 4 doses of RTS
Travelers can import colistin-resistant <em>enterobacteriaceae</em> including those possessing the plasmid-mediated <em>mcr-1</em> gene (Publications)
an overnight enrichment and CHROMagar Orientation plates supplemented with colistin, four people (10.5%) were found colonized with colistin-resistant Escherichia coli One cephalosporin-susceptible ST10 strain
A new antifungal and antiprotozoal bibenzyl derivative from<em> Gavilea lutea</em> (Publications)
together with two glycosylated flavonoids (1 and 2), batatasin III (3) and the phenanthrene isohircinol (5) were isolated from the aerial parts of Gavilea lutea. Their structures were elucidated on the basis
Novel 4-[4-(4-methylpiperazin-1-yl)phenyl]-6-arylpyrimidine derivatives and their antitrypanosomal activities against <em>T.brucei</em> (Publications)
with promising antitrypanosomal activity. In particular, 32 exhibits an in vitro EC(50) value of 0.5 µM against Trypanosoma brucei rhodesiense, and analogues 29, 30 and 33 show antitrypanosomal activities
Antitrypanosomal triterpenoid with an epsilon-lactone E-ring from <em>Salvia urmiensis</em> (Publications)
epsilon-lactone E-ring. The compound showed in vitro antitrypanosoal activity with an IC50 value of 5.6 muM against the Trypanosoma brucei rhodesiense STIB 900 strain and a selectivity index of 33. A possible
Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts... (Publications)
Italy. PARTICIPANTS: 100 166 people were enrolled from 1997 to 2007 and followed for an average of 11.5 years. Participants were free from previous coronary events at baseline. MAIN OUTCOME MEASURES: Modelled
Identification of a potential antimalarial drug candidate from a series of 2-aminopyrazines by optimization of aqueous solubility and potency across... (Publications)
Introduction of water-solubilizing groups on the 5-phenyl ring of a 2-aminopyrazine series led to the identification of highly potent compounds against the blood life-cycle stage of the human malaria parasite