Dynamics of <em>Schistosoma haematobium</em> egg output and associated infection parameters following treatment with praziquantel in school-aged... (Publications)
of infection-associated parameters decreased after treatment, reaching a minimum of 2.4% in weeks 5 (proteinuria) and 7 (leukocyturia) post-treatment, and 16.3% at the end of week 8 (microhaematuria) [...] additional tool for evaluating treatment outcomes in areas with high endemicity, preferably at weeks 5 and 6 post-treatment. The delayed decrease of microhaematuria confirms that lesions in the urinary tract
Increasing blood flow increases kt/V(urea) and potassium removal but fails to improve phosphate removal (Publications)
removal only improved from 28.1 +/- 1.3 to 31.4 +/- 1.5 (p = 0.050) when Qb was increased from 200 to 250 ml/min but remained unchanged at 31.2 +/- 1.5 mMol (NS compared to phosphate removal at Qb = 250 ml/min)
Direct costs of schizophrenia in Italian community psychiatric services (Publications)
56.3% of the total cost, daycare centre days for between 11.3 and 35.5%, home visits for 7.8 to 16.4%, and day-hospital days for 5.4 to 32.8%. Antipsychotics and anxiolytics were the most prescribed drugs
Effectiveness and profitability of preventive veterinary interventions in controlling infectious diseases of ruminant livestock in sub-Saharan Africa:... (Publications)
livestock diseases. The effectiveness and/or profitability of antimicrobial treatment (n = 5), test and slaughter (n = 5), and use of lay animal health workers (n = 1) applied exclusively, were evaluated in
Cross-sectional study of nutritional intake among patients undergoing tuberculosis treatment along the Myanmar-Thailand border (Publications)
on based on historical patient records. Out of a total of 28 participants, 20 (71.4%) were men and 5 (17.9%) were co-infected with HIV. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome compared [...] patients supplementing their rations. Mean treatment length at time of survey was 20.7 weeks (95% CI: 16.5 to 24.8). A significantly higher proportion of women (8/8, 100%) met caloric requirements compared with
Temporal distribution of <em>Plasmodium falciparum </em>recrudescence following artemisinin-based combination therapy: an individual participant data... (Publications)
3703 recurrent infections were detected in 60 studies conducted in Africa (15,512 children aged < 5 years) and 23 studies conducted in Asia and South America (5272 patients of all ages). Using molecular [...] dihydroartemisinin-piperaquine (DP) efficacy trial in Africa was 47% [95% CI 19-90%] in children under 5 years old treated with > 48 mg/kg total piperaquine (PIP) dose and 9% [95% CI 0-22%] in those treated
Global diversity and balancing selection of 23 leading <em>Plasmodium falciparum </em>candidate vaccine antigens (Publications)
structure of leading vaccine candidate antigens of P. falciparum using the MalariaGEN Pf3K (version 5.1) resource, comprising more than 2600 genomes from 15 malaria endemic countries. A stringent variant [...] encoding 23 leading and novel candidate malaria vaccine antigens including csp, trap, eba175, ama1, rh5, and CelTOS. Our analysis shows that current malaria vaccine formulations are based on rare haplotypes
Severe dental fluorosis in juvenile deer linked to a recent volcanic eruption in patagonia (Publications)
November 2012. We show that tephra caused severe dental fluorosis, with bone fluoride levels up to 5,175 ppm. Among subadults, tephra caused pathologic development of newly emerging teeth typical of fluorosis [...] highly susceptible to fluorosis, with average bone level increasing over 38-fold during the first 15.5 mo of exposure to tephra. This is the first report of fluorosis in wild ungulates from a volcanic eruption
Evaluation of farm-level parameters derived from animal movements for use in risk-based surveillance programmes of cattle in Switzerland (Publications)
METHODS: A framework was developed to select farms for surveillance based on a risk score summarizing 5 parameters. The proposed framework was validated using data from the bovine viral diarrhoea (BVD) s [...] parameters. Different cut offs; 50, 90, 95 and 99 %, were explored. The final scores ranged between 0 and 5. Validation of the scores against results from the BVD surveillance programme 2013 gave promising results
Discrepancy in plasma melarsoprol concentrations between HPLC and bioassay methods in patients with <em>T. gambiense</em> sleeping sickness indicates... (Publications)
samples were obtained before the first melarsoprol injection, immediately after and at 1 h, 24 h and 5 days after the 4th injection. Urine was collected before melarsoprol therapy and at 24 h after the 4th [...] as HPLC assays but at 1 h they were 4-65-fold higher than the levels assessed by HPLC. Even 24 h and 5 days after the 4th injection there was significant but decreasing activity. Urine levels were 40-260-fold