Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood (Publications)
in life, such as regulatory T (Treg) cells. OBJECTIVE: We sought to assess whether Treg cells from 4.5-year-old children from the Protection against Allergy: Study in Rural Environments birth cohort study [...] CONCLUSIONS: Farm milk exposure was associated with increased Treg cell numbers on stimulation in 4.5-year-old children and might induce a regulatory phenotype early in life, potentially contributing to
Discrepancy in plasma melarsoprol concentrations between HPLC and bioassay methods in patients with <em>T. gambiense</em> sleeping sickness indicates... (Publications)
samples were obtained before the first melarsoprol injection, immediately after and at 1 h, 24 h and 5 days after the 4th injection. Urine was collected before melarsoprol therapy and at 24 h after the 4th [...] as HPLC assays but at 1 h they were 4-65-fold higher than the levels assessed by HPLC. Even 24 h and 5 days after the 4th injection there was significant but decreasing activity. Urine levels were 40-260-fold
Increasing blood flow increases kt/V(urea) and potassium removal but fails to improve phosphate removal (Publications)
removal only improved from 28.1 +/- 1.3 to 31.4 +/- 1.5 (p = 0.050) when Qb was increased from 200 to 250 ml/min but remained unchanged at 31.2 +/- 1.5 mMol (NS compared to phosphate removal at Qb = 250 ml/min)
Schistosomiasis and soil-transmitted helminth control in Niger: cost effectiveness of school based and community distributed mass drug administration (Publications)
large scale schistosomiasis and soil-transmitted helminths control programme targeting children aged 5-14 years and adults. In two years 4.3 million treatments were delivered in 40 districts using school [...] Differences at sub-district are more marked. This is partly explained by the fact that a CDD treats 5.8 people for every one treated in school. The range in cost effectiveness for both direct and direct
Sequence conservation in <em>Plasmodium falciparum</em> á-helical coiled coil domains proposed for vaccine development (Publications)
promising immunological results 5 of these peptides were selected for further analysis. Direct sequencing of field samples from Papua New Guinea and Tanzania showed that 3 out of these 5 peptides were completely
Local perceptions of cholera and anticipated vaccine acceptance in Katanga province, Democratic Republic of Congo (Publications)
form of praying for healing were positively associated with anticipated OCV acceptance if costs of USD 5 were assumed. Conversely, respondents who feared negative social implications of cholera were less likely [...] respondents who generated their income through fishing. With an increase of assumed costs to USD 10.5, fear of financial constraints was negatively associated as well. CONCLUSIONS: Results suggest a high
Dynamics of <em>Schistosoma haematobium</em> egg output and associated infection parameters following treatment with praziquantel in school-aged... (Publications)
of infection-associated parameters decreased after treatment, reaching a minimum of 2.4% in weeks 5 (proteinuria) and 7 (leukocyturia) post-treatment, and 16.3% at the end of week 8 (microhaematuria) [...] additional tool for evaluating treatment outcomes in areas with high endemicity, preferably at weeks 5 and 6 post-treatment. The delayed decrease of microhaematuria confirms that lesions in the urinary tract
Determining treatment needs at different spatial scales using geostatistical model-based risk estimates of schistosomiasis (Publications)
population if country-level schistosomiasis prevalence estimates are considered, and 81.5 million treatments (50% CI: 67.3-107.5 million) if estimation is based on a more refined spatial scale at the provincial
Associations between family-related factors, breakfast consumption and BMI among 10- to 12-year-old European children: the cross-sectional... (Publications)
mean BMI-z-score = 0.4+/-1.2) and one of their parents (n = 6374; mean age = 41.4+/-5.3 years, 82.7% female, mean BMI = 24.5+/-4.2 kg/m(2)) were recruited from schools in eight European countries (Belgium
Study protocol: improving newborn survival in rural southern Tanzania: a cluster-randomised trial to evaluate the impact of a scaleable package of... (Publications)
000 households in 5 of the 6 study districts to estimate baseline mortality and prevalence of newborn care behaviours, ii) an adequacy survey in 2011 in a representative sample of 5,000 households to estimate