Elektromagnetische Felder des Mobilfunks im Zuge des aktuellen 5G-Netzausbaus Technische Aspekte und biologische Wirkungen im unteren Frequenzbereich... (Publications)
wurde in Deutschland im Jahr 2019 mit der Einführung des Mobilfunks der fünften Generation (5G) begonnen. Der 5G-Mobilkommunikationsstandard wird als Kerntechnologie für die Digitalisierung der Industrie [...] 7 Gigahertz (Frequency Range 1, FR1), der auch in den aktuellen 5G-Netzen genutzt wird. Zusätzlich werden besondere technische Aspekte der neuen 5G-Technologie betrachtet und ihre Auswirkungen auf die zu erwartende [...] erwartende Hochfrequenzimmission und die Exposition der Bevölkerung...
Immediate surgery compared with short-course neoadjuvant gemcitabine plus capecitabine, FOLFIRINOX, or chemoradiotherapy in patients with borderline... (Publications)
types of short-course neoadjuvant therapy compared with immediate surgery. METHODS: ESPAC5 (formerly known as ESPAC-5f) was a multicentre, open label, randomised controlled trial done in 16 pancreatic centres [...] cycles); or neoadjuvant capecitabine-based chemoradiation (total dose 50.4 Gy in 28 daily fractions over 5.5 weeks [1.8 Gy per fraction, Monday to Friday] with capecitabine 830 mg/m(2) twice daily [Monday to
Salidroside pretreatment alleviates PM2.5 caused lung injury via inhibition of apoptosis and pyroptosis through regulating NLRP3 inflammasome (Publications)
conditions. To uncover the possible therapy for PM(2.5) related pulmonary disease, we evaluated the protective role of Sal pre-treatment on PM(2.5) induced lung injury in mice by utilizing the survival [...] findings strongly indicated Sal as an effective precaution against PM(2.5) induced lung injury. Pre-administration of Sal before PM(2.5) treatment reduced the mortality within 120 h and alleviated inflammatory [...] PM(2.5) treatment via regulating Bax/Bcl-2/caspase-3 and...
The air and viruses we breathe: assessing the effect the PM2.5 air pollutant has on the burden of COVID-19 (Publications)
burden of respiratory viral diseases. We assessed the effect of increasing exposure to PM2.5 (particulate matter ≤ 2.5 microns in diameter) on SARS-CoV-2 susceptibility or COVID-19 severity and projected the [...] population show that if exposure affects severity, then hospital admissions are projected to increase by 5–10% for a one-unit exposure increase. However, if exposure affects susceptibility, then infections would [...] respond to changing air pollution levels. It is also important to...
Estimating urban <em>PM</em>10 and <em>PM</em>2.5 concentrations, based on synergistic MERIS/AATSR aerosol observations, land cover and morphology... (Publications)
approaches for quantitative estimation of daily mean Particulate Matter (PM) concentrations. Both fine (PM2.5) and coarse (PM10) concentrations were estimated over the area of London (UK) for the 2002–2012 time
A satellite-based spatio-temporal machine learning model to reconstruct daily PM2.5 concentrations across Great Britain (Publications)
matter (PM2.5) levels across Great Britain between 2008–2018. This high-resolution model consists of random forest (RF) algorithms applied in four stages. Stage-1 augments monitor-PM2.5 series using [...] spatial and spatio-temporal variables to build a prediction model for PM2.5. Stage-4 applies Stage-3 models to estimate daily PM2.5 concentrations over a 1 km grid. The RF architecture performed well in all [...] epidemiological analyses to assess health risks associated with both short- and...
NO2 and PM2.5 exposures and lung function in Swiss adults: estimated effects of short-term exposures and long-term exposures with and without... (Publications)
-18.5 ml [-26.5, -10.5]). A 10mug/m3 increase in 1-y mean NO2 was also associated with lower FEV1 (-7.7 ml; -15.9, 0.5) and FVC (-21.6 ml; -31.9, -11.4), as was a 10mug/m3 increase in 1-y mean PM2.5 (FEV1: [...] dioxide (NO2) and particulate matter with an aerodynamic diameter of less than or equal to 2.5. microns (PM2.5) exposures on lung function has been investigated mainly in children and less in adults. Furthermore [...] NO2 and PM2.5 on the day of the pulmonary function test was associated...
The association of LUR modeled PM2.5 elemental composition with personal exposure (Publications)
predicting personal exposures. In this study, the association of LUR modeled concentrations of PM2.5 components with measured personal concentrations was determined. The elements of interest were copper [...] sites were selected in each city (15 participants per city). Outdoor, indoor and personal 96-hour PM2.5 samples were collected by the participants over periods of two weeks in three different seasons (winter [...] with measured personal Cu exposure. After excluding observations with an...
Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines (Publications)
bis-O-acetoxyamidoxime of 5a in glacial acetic acid gave the saturated analogue 2,6-bis[4-(amidinophenyl)]-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine 8. O-Methylation of the amidoximes 5a-d gave the N-methoxyamidines [...] 2-amino-5-bromopyridines to yield 3a-d. Suzuki coupling of 3a-d with 4-cyanophenylboronic acid yielded the 2,6-bis(4-cyanophenyl)-imidazo[1,2-a]pyridine derivatives 4a-d. The bis-amidoximes 5a-d, obtained
Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents (Publications)
2-[5-(4-Amidinophenyl)-furan-2-yl]-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridi ne-6-carboxamidine acetate salt (7) was synthesized from 2-[5-(4-cyanophenyl)-furan-2-yl]-imidazo[1,2-a]pyridine-6-carbonitrile [...] hyl acetate. N-Methoxy-2-(5-[4-(N-methoxyamidino)-phenyl]-furan-2-yl)-imidazo[1,2-a]pyr idine-6-carboxamidine (6) was prepared via methylation of the respective diamidoxime 5a with dimethyl sulfate. By [...] of 2-acetylfuran first with N-bromosuccinimide, and second with bromine to form...
