Detection of arsenical drug resistance in <em>Trypanosoma brucei</em> with a simple fluorescence test [Research letters] (Publications)
transporter responsible for drug uptake. The same transporter carries the fluorescent diamidine DB99 (2,5-bis-(4-amidinophenyl)-3,4-dimethylfuran) into trypanosomes. The two DNA-containing structures in the
IV thrombolysis and renal function (Publications)
without IVT treatment served as a comparison group. RESULTS: Among 4,780 IVT-treated patients, 1,217 (25.5%) had a low GFR (
Exposure to radio-frequency electromagnetic fields from broadcast transmitters and risk of childhood cancer: a census-based cohort study (Publications)
conducted a time-to-event analysis including children under age 16 years living in Switzerland on December 5, 2000. Follow-up lasted until December 31, 2008. Second, all children living in Switzerland for some
Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents (Publications)
strains of the malarial parasite Plasmodium falciparum. Most of these derivatives showed a 4-49 and 5-17-fold increase in activity against NF54 and KI strains, respectively, as compared to FA and had a
Novel nucleoside-based antimalarial compounds (Publications)
contrast to de novo biosynthesis that is utilized by the human host. A series of twenty-two 2-, 6- and 5'-modified adenosine ribonucleosides was synthesized, with the expectation that these compounds would
New derivatives of bicyclic diamines with antiprotozoal activity (Publications)
omega-Aminoacyl and -alkyl derivatives of 4-(dialkylamino)bicyclo[2.2.2]octan-2-amines and of 5-(dialkylamino)-2-azabicyclo[3.2.2]nonanes were prepared and their activities were examined in vitro against
The silent burden of anaemia in Tanzanian children: a community-based study (Publications)
document the prevalence, age-distribution, and risk factors for anaemia in Tanzanian children less than 5 years old, thereby assisting in the development of effective strategies for controlling anaemia. METHODS:
Soudanones A-G: antifungal isochromanones from the ascomycetous fungus <em>Cadophora</em> sp. isolated from an iron mine (Publications)
six known analogues including 10 and 11 were isolated from a culture of the fungus Cadophora sp. 10-5-2 M, collected from the subterranean 10th level of the Soudan Underground Iron Mine in Minnesota. All
Cultivation of procyclic trypomastigotes of <em>Trypanosoma congolense</em> in a semi-defined medium with direct adaptation from bloodstream forms (Publications)
transformed into procyclic trypomastigotes. Established cultures of the procyclic forms yielded up to 4.5 X 10(7) parasites/ml. The cultivated populations consisted only of trypomastigotes and were not infective
Urban background particulate matter and allergic sensitization in adults of ECRHS II (Publications)
and blood tests conducted for the measurement of specific immunoglobulin E. Fine particle mass (PM(2.5),