Few associations between high-sensitivity C-reactive protein and environmental factors in 4.5-year-old children (Publications)
C-reactive protein (hsCRP) at the age of 4.5 years. Methods: The high-sensitivity CRP values (n = 653) and serum-specific IgE concentrations were measured from 4.5-year-old children in rural areas in five [...] (aOR 2.51 95% CI 1.12-5.59). Conclusion: We found few associations between early environmental farming factors and hsCRP levels, and between hsCRP levels and atopic sensitization in 4.5-year-old children. [...] Group. Few associations between high-sensitivity C-reactive protein and...
Oxidative properties of ambient PM2.5 and elemental composition: Heterogeneous associations in 19 European cities (Publications)
extent to which constituents of PM2.5 (transition metals, sodium, chloride) contribute to the ability to generate hydroxyl radicals ((OH)-O-center dot) in vitro in PM2.5 sampled at 20 locations in 19 European [...] European centres participating in the European Community Respiratory Health Survey. PM2.5 samples (n = 716) were collected on filters over one year and the oxidative activity of particle suspensions obtained
Antitrypanosomal activity of 5-nitro-2-aminothiazole-based compounds (Publications)
A small series of 5-nitro-2-aminothiazole-based amides containing arylpiperazine-, biphenyl- or aryloxyphenyl groups in their core were synthesized and evaluated as antitrypanosomatid agents. All tested
Elemental composition and oxidative properties of PM2.5 in Estonia in relation to origin of air masses - results from the ECRHS II in Tartu (Publications)
Fine particulate matter (PM(2.5)) was sampled at an urban background site in Tartu, Estonia over one-year period during the ECRHS II study. The elemental composition of 71PM(2.5) samples was analyzed for different [...] oxidative properties were correlated to the origin of air masses. The OH values were approximately 1.5 times higher when air masses originated from the direction of "Eastern Europe" or "Russia." The origin [...] measured particles was evaluated using principal component factor...
Immunologic-based diagnosis of latent tuberculosis among children less than 5 years of age exposed and unexposed to tuberculosis in Tanzania:... (Publications)
those with and without exposure: 20% (38/186) vs. 20% (23/115) QFT-positive, and 2% (4/186) vs. 4% (5/115) indeterminate QFT. QFT conversion rate was 7% (22 children) and reversion 8% (25 children). Of
Alkyl and dialkylaminoethyl derivatives of 5-amino-2-azabicyclo[3.2.2]nonanes and their antiplasmodial and antitrypanosomal activities (Publications)
N-Alkyl and N-(2-dialkylaminoethyl) derivatives of 5-amino-2-azabicyclo-nonanes were prepared and tested in vitro for their activities against the multidrug-resistant K1 strain of Plasmodium falciparum