<em>Trypanothione reductase</em> high-throughput screening campaign identifies novel classes of inhibitors with anti-parasitic activity (Publications)
chemical classes of trypanothione reductase (TR) inhibitors worthy of further investigation. Hits from 5 of these chemical classes have been developed further through different combinations of preliminary
Medicaid family planning waivers in 3 states: did they reduce unwanted births? (Publications)
difference-in-differences approach. Waivers in New York and Illinois were associated with almost a 5.0 percentage point reduction in unwanted births among adults and with a 7 to 8.0 percentage point reduction
Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents (Publications)
exploiting molecular hybridization between the potent cruzain inhibitors (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-bromophenyl)prop-2-en-1-one and (E)-3-hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)-7-m
High prevalence of <em>Strongyloides stercoralis</em> among school children in rural Côte d'Ivoire (Publications)
Two cross-sectional surveys were carried out in rural Cote d'Ivoire, the first in 5 primary schools in the Lake Taabo area, and the second in the primary school of Azaguie-Institute de Recherche sur les
Unique modifications of translation elongation factors (Publications)
proteins carrying these modifications, elongation factor 1A, elongation factor 2 and initiation factor 5A, are all involved in elongation steps of translation. For diphthamide and, in part, hypusine, functional
Provider-patient interaction in rural Cameroon: how it relates to the patient's understanding of diagnosis and prescribed drugs, the patient's concept... (Publications)
related to the extent of clarity a provider used in mentioning it during consultation (recall rates: 87.5% if mentioned explicitly, 56.7% if mentioned indirectly and 19.2% if not mentioned at all; p
The use of acoustic reflectometry in the study of middle ear effusion in children suffering from acute otits media, upper respiratory tract infection... (Publications)
= 81) as well as in healthy control children (n = 152). Data are reported in age categories 0-4 and 5-13 years. Middle ear effusion was found in 86% of children with acute otitis media, 49% of children
Parallel synthesis of a series of non-functional ATP/NAD analogs with activity against trypanosomatid parasites (Publications)
substituents, 15 new ATP/NAD analogs were obtained in screening quantities. In these compounds, a 5'-desoxyadenosine moiety was conserved as key molecular recognition motif. The inhibition of P. falciparum
Unique modifications of translation elongation factors (Publications)
proteins carrying these modifications, elongation factor 1A, elongation factor 2 and initiation factor 5A, are all involved in elongation steps of translation. For diphthamide and, in part, hypusine, functional
High prevalence of <em>Strongyloides stercoralis</em> among school children in rural Côte d'Ivoire (Publications)
Two cross-sectional surveys were carried out in rural Cote d'Ivoire, the first in 5 primary schools in the Lake Taabo area, and the second in the primary school of Azaguie-Institute de Recherche sur les