Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound (Publications)
ne isomer, isoneocryptolepine (4), and a quaternary derivative, N-methyl-isocryptolepinium iodide (5). The latter compounds showed a high antiplasmodial activity against the chloroquine-resistant Plasmodium
Artemether, artesunate, praziquantel and tribendimidine administered singly at different dosages against <em>Clonorchis sinensis</em>: acomparative in... (Publications)
d to rats infected with adult C. sinensis, resulted in mean worm burden reductions of 100, 100, 89.5 and 80.7%, respectively (all P
Cinnamoylphenethyl amides from <em>Polygonum hyrcanicum</em> possess anti-trypanosomal activity (Publications)
but less active compounds, such as cannabisin B (2), tyrosol (3), p-coumaric acid (4), ferulic acid (5), and N-cis-feruloyltyramine (6) were also identified, along with N-trans-3,4-dimethoxycinnamoyldopamine
<em>Schistosoma haematobium</em> egg excretion does not increase after exercise: implications for diagnostic testing (Publications)
positivity for S. haematobium (25.7% versus 23.0%, P = 0.31) and mean egg counts (10.2 eggs/10 mL versus 8.5 eggs/10 mL, P = 0.45) did not differ. Exercise before urine collection does not appear to increase S
Cardiovascular diseases risk factors among recently arrived Eritrean refugees in Switzerland (Publications)
two (2%) had a low density lipoprotein (LDL) cholesterol > /= 4.1 mmol/l. Among the 48 participants (5 females, 43 males) followed, there were no significant changes in cardiovascular risk profile 1 year
Genotypic and phenotypic diversity of <em>Mycobacterium tuberculosis</em> complex genotypes prevalent in West Africa (Publications)
West Africa. Thirty-six whole genome sequenced drug susceptible MTBC isolates belonging to lineages 4, 5 and 6 were included in this study. The isolates were phenotypically characterized for urease activity
New 2‑aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities (Publications)
were prepared from acyclic starting materials, benzylidene acetones and ammonium thiocyanates, via 5 steps, including ring closure, aromatization, S-methylation, oxidation to methylsulfonyl compounds,
Cattle productivity under traditional village husbandry system in Sellale, Central Ethiopia: a four and a half year herd follow-up (Publications)
We conducted a longitudinal cattle productivity survey over 4.5 years amongst 20 traditional small-holder farms which included 794 cattle, in Sellale, Central Ethiopia. Upgraded high yield cattle (Holstein
Antiprotozoal activity of bicyclic diamines with a N-methylpiperazinyl group at the bridgehead atom (Publications)
omega-Aminoacyl and -alkyl derivatives of 4-(4-methylpiperazin-1-yl)bicyclo[2.2.2]octan-2-amines and of 5-(4-methylpiperazin-1-yl)-2-azabicyclo[3.2.2]nonanes were prepared and their activities were examined
Influenza pandemics and tuberculosis mortality in 1889 and 1918: analysis of historical data from Switzerland (Publications)
100 influenza deaths (per 100,000 population) monthly PTB mortality rates increased by a factor of 1.5 (95%Cl 1.4-1.6, p
