Pumilanol, an antiprotozoal isoflavanol from Tephrosia pumila47 (Publications)
A novel isoflavan-4-ol (pumilanol), (rel)-3 beta-(2'-hydroxy-4',5'-methylenedioxyphenyl)-6-methoxy-4 alpha,7-dihydroxybenzo-3,4-dihydropyran (1) and two known flavonoids, tephrinone (2) and rotenone (3)
Ukrainian-Swiss Mother and Child Health Programme, 2011- 2015 (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/ukrainian-swiss-mother-and-child-health-programme-2011-2015
infant mortality decreased in 1.5-2.5 times, and the percent of physiological deliveries increased twice. On a country level, Ukraine declared the achievement of MDG 4 and 5 in the end of 2013. Target Groups
Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis (Review) (Publications)
all-cause mortality, both overall (risk ratio (RR) 0.89, 95% confidence interval (CI) 0.75 to 1.05; 5 RCTs, 9932 participants, moderate-certainty evidence), and restricted to studies with six-month follow-up [...] mortality in participants known to be infected with HIV (odds ratio (OR) 0.80, 95% CI 0.67 to 0.96; 5 RCTs, 5855 participants; moderate-certainty evidence). It is uncertain whether Xpert MTB/RIF has no [...] on the proportion of participants who were treated for tuberculosis (RR 1.10,...
Mining Sudanese medicinal plants for natural compounds against malaria and neglected tropical diseases (Publications)
Rutaceae. Nectandrin B exhibited the highest activity against L. donovani (IC50 4.5 µM) and the highest selectivity index (25.5). Given the urgent need for better drugs and the fact that mycetoma is the most [...] From this screening, niclosamide showed interesting activity with a minimal inhibitory concentration ˂5 µM. Furthermore, additional niclosamide analogues were tested for proof of concept. The tested compounds
Report actuelles (Page)
https://www.swisstph.ch/fr/projects/ludok/aktuelle-berichte
quelles sont les conséquences sanitaires de la pollution et quel est le niveau de conformité. En plus des 5 polluants classiques, le rapport considère également les PUNR, la suie, et d'autres polluants réglementés [...] Le projet GeLuft a calculé en parallèle que le respect des valeurs indicatives de l'OMS pour les PM2.5 et le NO2 en Suisse permettrait d'éviter plus de 3300 décès prématurés et 3400 cas d'asthme par rapport [...] Meta-analysis of selected health effects of long-term exposure to...
Mining Sudanese medicinal plants for natural compounds against malaria and neglected tropical diseases (Publications)
Rutaceae. Nectandrin B exhibited the highest activity against L. donovani (IC50 4.5 µM) and the highest selectivity index (25.5). Given the urgent need for better drugs and the fact that mycetoma is the most [...] From this screening, niclosamide showed interesting activity with a minimal inhibitory concentration ˂5 µM. Furthermore, additional niclosamide analogues were tested for proof of concept. The tested compounds
Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis (Review) (Publications)
all-cause mortality, both overall (risk ratio (RR) 0.89, 95% confidence interval (CI) 0.75 to 1.05; 5 RCTs, 9932 participants, moderate-certainty evidence), and restricted to studies with six-month follow-up [...] mortality in participants known to be infected with HIV (odds ratio (OR) 0.80, 95% CI 0.67 to 0.96; 5 RCTs, 5855 participants; moderate-certainty evidence). It is uncertain whether Xpert MTB/RIF has no [...] on the proportion of participants who were treated for tuberculosis (RR 1.10,...
Outbreak of <em>Cryptosporidium hominis</em> following river flooding in the city of Halle (Saale), Germany, August 2013 (Publications)
95%-CI: 0.9-7.6). In multivariable analysis visits to the floodplain remained the sole risk factor (OR: 5.5; 95%-CI: 1.4-22). Only C.hominis of a single genotype (IbA9G2) was detected in stools. Oocysts were
Differential impact of malaria control interventions on <em>P. falciparum</em> and <em>P. vivax</em> infections in young Papua New Guinean children (Publications)
during (2008) and after scale-up of control interventions (2013). In each cohort, children aged 1-5 years were actively monitored for infection and illness. Incidence of malaria episodes, molecular force [...] vivax clinical episodes declined at rates comparable to P. falciparum between 2006, 2008 and 2013 (IR 2.5 to 1.1 to 0.2), while P. vivax molFOB (2006, 9.8; 2008, 12.1) and prevalence (2006, 59.6%; 2008, 65
State of deworming coverage and equity in low-income and middle-income countries using household health surveys: a spatiotemporal cross-sectional... (Publications)
preschool children was estimated at 33.0% (95% CI 32.9-33.1). The subnational coverage ranged from 0.5% to 87.5%, and within-country variation was greater than between-country variation. Of the 31 countries
