Discovery of an orally active nitrothiophene-based antitrypanosomal agent (Publications)
trypanosomes and are metabolically stable. One of the compounds, (E)-N-(4-(methylamino)-4-oxobut-2-en-1-yl)-5-nitrothiophene-2-carboxamide (10), selectively inhibited the growth of T. b. brucei, T. b. gambiense
"Flexible lockdown" in Switzerland individual responsibility and the daily navigation of risk and protection (Publications)
This chapter focuses on this small, multilingual, mountainous country of 8.5 million inhabitants. It presents the preliminary results of a medical anthropology study called SociocoViD, which was developed
Revolutionizing the public health workforce: a policy brief in retrospect of the World Congress on Public Health, Rome 2020 (Publications)
and work opportunities; 4. Overcoming the paradoxical shortage and overproduction of graduates and 5. Developing adaptable, multisectoral agents of change.Conclusion: Public health education of the future
Nachtlärminduzierte Schlafstörungen und Herz-Kreislauf-Risiko (Publications)
noise (road traffic, railway, aircraft and industrial noise) causes severe sleep disorders among 6.5 million people in Europe. New epidemiological and mechanistic field studies show that in particular
3-Hydroxy-propanamidines, a new class of orally active antimalarials targeting <em>Plasmodium falciparum</em> (Publications)
chloroquine-sensitive and multidrug-resistant parasite strains ofPlasmodium falciparum (with IC50 values of 5 and 12 nM against 3D7 and Dd2 strains, respectively) as well as low cytotoxicity in human cells. In
Synthesis and in vitro antimalarial testing of neocryptolepines: SAR study for improved activity by introduction and modifications of side chains at... (Publications)
17i showed an IC50 of 2.2 nM for CQR (K1), a selectivity index of 1243 and a resistance index of 0.5
Intersectoral collaboration between the medical and veterinary professions in low-resource societies: the role of research and training institutions (Publications)
y affect human health in low-resource countries. A symposium was organised in Antwerp, Belgium, on 5 November 2010 to evaluate how intersectoral collaboration among educational and research institutions
Gastrointestinal parasite egg excretion in young calves in periurban livestock production in Mali (Publications)
. We found eggs of Strongyloides papillosus (Age class 0-1 month: prevalence 39%, 2-3 months: 59%, 5-6 months: 42%), strongyles (14%, 24%, 36%), coccidian oocysts (37%, 68%, 64%) and at low prevalence
Contribution of influenza immunity and virosomal-formulated synthetic peptide to cellular immune responses in a phase I subunit malaria vaccine trial (Publications)
falciparum apical membrane antigen-1 (AMA-1) was observed with stimulation indices ranging from 2 to 4.5. All volunteers showed pre-existing IRIV specific cellular immunity assessed by ex vivo IFN-gamma ELISpot
Evaluation des VNTR (variable number of tandem repeats) des isolats de <em>Mycobacterium bovis</em> en Algérie (Publications)
discriminatory potency of variable number of tandem repeats (VNTR), based on 7 loci (MIRU 26, 27 and 5 ETRs A, B, C, D, E) was assayed on Mycobacterium bovis strains obtained from samples due to tuberculosis