Prevalence and risk factors for carriage of multi-drug resistant <em>Staphylococci</em> in healthy cats and dogs (Publications)
with an increased risk of colonisation by multi-drug resistant Staphylococci (OR = 2.4, 95% CI: 1.1 5.2, p value LRT = 0.04). When identifying efficient control strategies against antibiotic resistance
Evaluating decontamination protocols for the isolation of <em>Mycobacterium ulcerans</em> from swabs (Publications)
potential decontamination agents for the isolation of M. ulcerans from swabs. RESULTS: Povidone iodine at 0.5 and 1% exhibited the lowest contamination and recovery rate for microbial contaminants and M. ulcerans
Rickettsial illnesses as important causes of febrile illness in Chittagong, Bangladesh (Publications)
and associated seasonality patterns. We diagnosed scrub typhus in 16.8% (70/416) and murine typhus in 5.8% (24/416) of patients; 2 patients had infections attributable to undifferentiated Rickettsia spp.
Combining PCR with microscopy to reduce costs of laboratory diagnosis of Buruli ulcer (Publications)
were negative in microscopic analysis. This stepwise approach reduced unit cost by more than 50% to $5.41, and the total costs were reduced from $917 to $433
Changing patterns of soil-transmitted helminthiases in Zanzibar in the context of national helminth control programs (Publications)
the prevalence of S. stercoralis, hookworm, A. lumbricoides, and T. trichiura decreased by 81.0%, 80.5%, 70.6%, and 48.6%, respectively. Infection intensities decreased by > 95% for all helminth species
RFX transcription factors are essential for hearing in mice (Publications)
essential and evolutionarily conserved regulators of the HC-specific transcriptomes, and detect Rfx1,2,3,5 and 7 in the developing HCs. To understand the role of RFX in hearing, we generate Rfx1/3 conditional
Host-directed therapies for tackling multi-drug resistant TB - learning from the Pasteur-Bechamp debates (Publications)
Tuberculosis (TB) remains a global emergency causing an estimated 1.5 million deaths annually. For several decades the major focus of TB treatment has been on antibiotic development targeting Mycobacterium
DNA replication fidelity in <em>Mycobacterium tuberculosis</em> is mediated by an ancestral prokaryotic proofreader (Publications)
DnaE1 itself encodes an editing function that proofreads DNA replication, mediated by an intrinsic 3'-5' exonuclease activity within its PHP domain. Inactivation of the DnaE1 PHP domain increases the mutation
Complement factor D, albumin, and immunoglobulin G anti-band 3 protein antibodies mimic serum in promoting rosetting of malaria-infected red blood... (Publications)
Complement factor D alone induced 30 to 40% of de novo rosetting. Its effect was additive to that of 0.5 mg/ml albumin and to that of 15 ng/ml of naturally occurring antibodies to the anion transport protein
Growth of mature beech in relation to ozone and nitrogen deposition: an epidemiological approach (Publications)
better for maximum rather than average exposure values. Coefficients indicated growth changes of -22.5% (14.3-28.6 confidence interval) and -35.1% (17.8-47.3) respectively per 10 ppm hours. These changes