Benefit-cost analysis of coordinated strategies for control of rabies in Africa (Publications)
countries and PEP would lead to the elimination of dog rabies in Africa with total welfare gains of USD 9.5 billion (95% CI: 8.1 - 11.4 billion) between 2024 and 2054 (30 years). Coordinated disease control between
Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies (Publications)
health related quality of life) and (4) multiple treatment comparisons (e.g. multi-arm studies); (5) "statistically very persuasive" results (p-values
Diversity, Equity and Inclusion (Page)
https://www.swisstph.ch/fr/about/careers/diversity-equity-and-inclusion
SDGs. The DEI Network aims to contribute to SDGs 3, 5, 10 and 17. Goals 3 - Ensure healthy lives and promote well-being for all at all ages Goals 5 - Achieve gender equality and empower all women and girls
Reduced Efficacy of Anthelmintic Drugs (Page)
https://www.swisstph.ch/fr/news/20170926-reduced-efficacy-of-anthelmintic-drugs
Reduced Efficacy of Anthelmintic Drugs 26.09.2017 Approximately 1.5 billion people worldwide are affected by soil-transmitted helminth infections. Efficacy of current treatments is decreasing, as indicated [...] September in the peer-reviewed journal BMJ. About soil-transmitted helminth infections Approximately 1.5 billion people are infected with at least one of the three types of soil-transmitted helminths: Ascaris
Cancer risk in adolescents and young adults living with HIV in South Africa: a nationwide cohort study (Publications)
including 429 who developed Kaposi sarcoma (30.0 per 100 000 person-years), 107 non-Hodgkin lymphoma (7.5 per 100 000 person-years), 48 Hodgkin lymphoma (3.4 per 100 000 person-years), 45 cervical cancer (3 [...] non-Hodgkin lymphoma (3.17, 2.06-4.89), Hodgkin lymphoma (4.83, 2.61-8.93), and leukaemia (unadjusted HR 5.90, 95% CI 2.87-12.12). Cancer rates decreased over the study period, driven by declining Kaposi sarcoma
Whole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of <em>Klebsiella oxytoca</em> group in invasive infections: a retrospective... (Publications)
cephalosporins than K. variicola isolates (odds ratio = 2.61, p = 0.003, 95% confidence interval [1.38,5.06]). K. oxytoca group isolates were found to be more likely associated with invasive infection to primary [...] sites than K. pneumoniae group isolates (odds ratio = 2.39, p = 0.0044, 95% confidence interval [1.05,5.53]). CONCLUSIONS: Currently misdiagnosed Klebsiella spp. can be distinguished using a ribosomal ma
Single blinded semi-field evaluation of MAÏA® topical repellent ointment compared to unformulated 20% DEET against <em>Anopheles gambiae</em>,... (Publications)
580.9 min (95% CI 571.1-590.7) against An. arabiensis; 444.1 min (95% CI 401.8-486.5) vs 436.9 min (95% CI 405.2-468.5) against Ae. aegypti. CONCLUSIONS: MAIA((R)) repellent ointment provides complete
Comparison of cone bioassay estimates at two laboratories with different <em>Anopheles </em>mosquitoes for quality assurance of pyrethroid... (Publications)
METHODS: Double-blinded bioassays were conducted on twenty unused pyrethroid ITNs of 4 brands (100 nets, 5 subsamples per net) that had been delivered for mass distribution in Papua New Guinea (PNG) having passed [...] mortality (M24) (rs = 0.9,p < 0.0001,n = 20) but BA showed systematic bias between the results. Of the 5 nets with discrepant result between IHI and PNGIMR, three had confidence intervals overlapping the 80%
Potential contribution of HIV during first-line tuberculosis treatment to subsequent rifampicin-monoresistant tuberculosis and acquired tuberculosis... (Publications)
tuberculosis, HIV positivity during previous treatment (adjusted OR 5.13, 1.61-16.32) was associated with uniqueness as was female sex (2.50 [1.18-5.26]). Interpretation: These data suggest that HIV contributes
The impact of soil transmitted helminth on malaria clinical presentation and treatment outcome: a case control study among children in Bagamoyo... (Publications)
species tended to be associated with increased risk of clinical malaria [OR = 3.0, 95% CI of 0.9-9.5]. In multiple conditional regression analysis, the overall protective effect was lower for all helminth [...] parasitemia to severe malaria, there was a 50% significant protective effect with overall helminths [OR = 0.5, 95% CI of 0.3-0.9]. On the contrary, hookworm species was highly predictive of uncomplicated and severe