Molecular epidemiology of pneumococci obtained from Gambian children aged 2-29 months with invasive pneumococcal disease during a trial of a 9-valent... (Publications)
BOX-PCR and MLST. RESULTS: Twenty-nine different serotypes were identified; serotypes 14, 19A, 12F, 5, 23F, and 1 were common and accounted for 58.3% of all serotypes overall. MLST analysis showed 72 sequence
Molecular and culture-based diagnosis of <em>Clostridium difficile</em> isolates from Côte d'Ivoire after prolonged storage at disrupted cold chain... (Publications)
for anaerobic culture, susceptibility testing, PCR assays and ribotyping. RESULTS: Sixteen samples (5.4%) had a positive GDH screening test. C. difficile infection was confirmed in six specimens by culture
The extended AT-hook is a novel RNA binding motif (Publications)
identified 80 human and 60 mouse eAT-hook proteins and biochemically characterized the eAT-hooks of Tip5/BAZ2A, PTOV1 and GPBP1. Microscale thermophoresis and electrophoretic mobility shift assays reveal the
Health & demographic surveillance system profile: the Taabo Health and Demographic Surveillance System, Côte d'Ivoire (Publications)
conducted to determine causes of death. Repeated cross-sectional epidemiological surveys on approximately 5-7% of the population and specific, layered-on haematological, parasitological and questionnaire surveys
Relationship between humoral response to <em>Plasmodium falciparum</em> merozoite surface antigen-2 and malaria morbidity in a highly endemic area of... (Publications)
IgG to FC27, 3D7, and d3D7 was 91%, 90%, and 90%, respectively. The majority of individuals > or = 5 years of age had antibodies to both forms of MSA-2. The geometric mean antibody units increased with
Novel inhibitors of <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase with anti-malarial activity in the mouse model (Publications)
A high throughput screen and subsequent medicinal chemistry program identified a series of N-alkyl-5-(1H-benzimidazol-1-yl)thiophene-2-carboxamides with low nanomolar in vitro potency against DHODH from
Treatment of cutaneous leishmaniasis among travellers (Publications)
Leishmaniasis is endemic in 88 countries on five continents. There are 1-1.5 million cases of cutaneous leishmaniasis reported yearly worldwide. There has been a sharp increase in recorded cases over the
Prevalence of airflow obstruction in smokers and never smokers in Switzerland (Publications)
tions of the Global Initiative for Chronic Obstructive Lung Disease.Prevalence of AO ranged from 2.5% in subjects aged 30-39 to 8.0% in those aged 70 or more. In multivariate analysis, age (ORaged70+ vs
Auswirkungen von Luftschadstoffen auf die Atemwege von Kleinkindern (Publications)
A one year study on a random sample of 1225 Swiss children aged 0-5 years was conducted in four different areas (two urban, one suburban and one rural) of Switzerland to investigate the relationship between
Muscle force up to 50% of maximum does not affect cutaneous silent periods in thenar muscles (Publications)
obtained from abductor pollicis brevis muscle following ipsilateral recurrent noxious digit 2 and digit 5 stimulation. RESULTS: Group average CSP onset and end latency, CSP duration, and the magnitude of EMG