Sociocultural context of suicidal behaviour in the Sundarban region of India (Publications)
were uncertain about their "intention to die," and pesticide poisoning was the commonest method (95.5%). Significant male-female differences were found with respect to education level, occupation, and venue
Household survey of pesticide practice, deliberate self-harm and suicide in the Sundarban region of west Bengal, India (Publications)
about safe storage of pesticides. The pesticide-related annual DSH rate was 158.1 (95% CI 126.2-195.5), and for suicide it was 73.4 (95% CI 52.2-100.3) per 100,000. Unsafe pesticide practice and psychosocial
Pulsed radio-frequency electromagnetic fields: dose-dependent effects on sleep, the sleep EEG and cognitive performance (Publications)
handset like signal) with a 10 g-averaged peak spatial specific absorption rate of (1) 0.2 W kg(-1), (2) 5 W kg(-1), or (3) sham exposed in a double-blind, crossover design. During exposure, subjects performed
Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against <em>Trypanosoma... (Publications)
2-{[3-(3-dimethylaminopropoxy)-2-oxo-2H-chromen-7-yl]oxy}anthracene-1,4-dione (10) showed an IC50 value of 5.4 muM against TbGAPDH and a concomitant Ki value of 2.32 muM against TcTR. Notably, 2-{4-[6-(2-dime
Approved oncology drugs lack <em>in vivo</em> activity against <em>Trichuris muris</em> despite <em>in vitro</em> activity (Publications)
adult worm stage (> 80 % drug effect at 50 muM), of which six revealed IC50 values between 1.8 and 5.0 muM. Except for tamoxifen citrate, all in vitro active drugs were protein kinase inhibitors. None
Limited genetic diversity of hepatitis B virus in the general population of the Offin River valley in Ghana (Publications)
countries, the other 33 formed a separate cluster distinguished by an intergroup mean distance of 1.5% from the pan-African HBV/E cluster. Successful implementation of HBV vaccination in the region was
Sensitivity of the point-of-care circulating cathodic antigen urine cassette test for diagnosis of <em>Schistosoma mansoni</em> in low-endemicity... (Publications)
haematobium were found in eight participants (1.2%), whereas the prevalence of microhematuria was 13.5%. A single POC-CCA urine cassette test revealed a several-fold higher prevalence of S. mansoni than
Diagnostic comparison between FECPAKG2 and the Kato-Katz method for analyzing soil-transmitted helminth eggs in stool (Publications)
At baseline FECPAKG2 revealed a sensitivity of 75.6% (72.0-77.7) for detecting A. lumbricoides, 71.5% (67.4-95.3) for hookworm and 65.8% (64.9-66.2) for T. trichiura, which was significantly lower (all
Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale (Publications)
significantly affect L-PZQ exposure in both studies. The model for AUC was then extrapolated to children 2-5 years old accounting for enzyme maturation and weight. The predicted exposures were compared to an external
Human monocytotropic ehrlichiosis: a systematic review and analysis of the literature (Publications)
(9.9%) and immunocompromized (16.3%) cases, and sequelae are rare (4.2% in immunocompetent cases, 2.5% in immunocompromised cases).