Synthesis, <em>in-vitro</em> antiprotozoal activity and molecular docking study of isothiocyanate derivatives (Publications)
exhibited antiplasmodial activity with IC50s in the range of 1.1-2.7microM and SI values between 1.1 and 14.5. The isothiocyanate derivative 7c showed against T. cruzi with an IC50 value of 1.9microM and SI 4.
Relative validation of a food frequency questionnaire to estimate food intake in an adult population (Publications)
group level from 0.09 (soup) to 0.92 (alcohol). Nine out of 25 food groups showed correlations > 0.5, indicating moderate validity. More than half the food groups were overestimated in the FFQ, especially
Implementation of tuberculosis intensive case finding, isoniazid preventive therapy, and infection control ("Three I's") and HIV-tuberculosis service... (Publications)
2012 at 47 sites in 26 countries: 6 (13%) Asia Pacific, 7 (15%), Caribbean, Central and South America, 5 (10%) Central Africa, 8 (17%) East Africa, 14 (30%) Southern Africa, and 7 (15%) West Africa. RESULTS:
Common variants in Mendelian kidney disease genes and their association with renal function (Publications)
entries, corresponding to mutations in 258 genes. We interrogated common SNPs (minor allele frequency > 5%) within these genes for association with the estimated GFR in 74,354 European-ancestry participants
Dog ecology, bite incidence, and disease awareness: a cross-sectional survey among a rabies-affected community in the Democratic Republic of the Congo (Publications)
officials, with a large proportion of free-roaming unvaccinated dogs. The annual dog bite incidence of 5.2 per 1000 person years was high, whereas community rabies knowledge was low resulting in poor practices
Fluorescence in situ hybridization (FISH) for rapid identification of <em>Salmonella</em> spp. from agar and blood culture broth--an option for the... (Publications)
of 97.4% for environmental Salmonella spp. isolates, and sensitivity of 100% and specificity of 99.5% for blood culture materials. CONCLUSIONS: FISH proved to be highly reliable for a rapid identification
Detection of second line drug resistance among drug resistant <em>Mycobacterium tuberculosis</em> isolates in Botswana (Publications)
isolates analyzed, 33 (58%) were MDR-TB, 4 (7%) were additionally resistant to flouroquinolones and 3 (5%) were resistant to both fluoroquinolones and second-line injectable drugs. The most common fluoroquinolone
Antenatal care and skilled delivery service utilization in Somali pastoral communities of eastern Ethiopia (Publications)
confounders. RESULTS: 27% [95%CI 22.8-31.2%] of women used antenatal care and 22.6% [95%CI 18.7-26.5%] received skilled delivery service. None of the respondents reported postnatal care. 43% reported that
Genome-wide association study identifies five loci associated with lung function (Publications)
variants at five additional loci: 2q35 in TNS1 (P = 1.11 x 10(-12)), 4q24 in GSTCD (2.18 x 10(-23)), 5q33 in HTR4 (P = 4.29 x 10(-9)), 6p21 in AGER (P = 3.07 x 10(-15)) and 15q23 in THSD4 (P = 7.24 x 10(-15))
Joint effect of obesity and TNFA variability on asthma: two international cohort studies (Publications)
more common G/G genotype, particularly among nonatopics (OR for G/A and A/A genotypes 6.1, 95% CI 2.5-14.4; OR for G/G genotype 1.7, 95% CI 0.8-3.3). The present findings provide, for the first time, evidence