Timeliness and completeness of vaccination and risk factors for low and late vaccine uptake in young children living in rural southern Tanzania (Publications)
DTP-3 and 296/643 (46%) for MCV-1. Coverage was lower for all vaccines except DTP-1 in children living .5 km from a healthcare facility. Delayed uptake was associated with poverty. Low and delayed MCV-1 vaccination
Association between serum vitamin D, retinol and zinc status, and acute respiratory infections in underweight and normal-weight children aged 6-24... (Publications)
children with zinc insufficiency and those that were serum retinol deficient had 1.2 (95% CI 1.0-1.5) times higher risk of URI and 1.9 (95% CI 1.4-2.6) times higher risk of ALRI, respectively. Thus, our
Joint effect of obesity and TNFA variability on asthma: two international cohort studies (Publications)
more common G/G genotype, particularly among nonatopics (OR for G/A and A/A genotypes 6.1, 95% CI 2.5-14.4; OR for G/G genotype 1.7, 95% CI 0.8-3.3). The present findings provide, for the first time, evidence
<em>Plasmodium falciparum</em>: cloned and expressed CIDR domains of PfEMP1 bind to chondroitin sulfate A (Publications)
binding using soluble CSA inhibited binding to CHO cells by up to 100% at 2 mg/ml and by 62.4% at 0.5 mg/ml, whereas 1 mg/ml heparan sulfate had only a little effect (18.1%). In contrast, a recombinant
Clinical aspects of 2541 patients with second stage human African trypanosomiasis (Publications)
malnutrition is significantly more frequently observed in children of all ages (43-56%) than in adults (23.5%)
Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation (Publications)
albeit with pronounced cytotoxicity. One dimer showed a MIC(99) value against M. tuberculosis of 2.5mug/ml. The alkylated eudistomin N and O derivatives displayed activities down to 18nM against P. falciparum
Associations between home- and family-related factors and fruit juice and soft drink intake among 10- to 12-year old children: the ENERGY project (Publications)
consumption). 7915 children (52% girls; mean age=11.7±0.8 years) and 6512 parents (83% women; mean age=41.4±5.3 years) completed the questionnaire. Multilevel regression analyses were used to examine the aforementioned
Approved oncology drugs lack <em>in vivo</em> activity against <em>Trichuris muris</em> despite <em>in vitro</em> activity (Publications)
adult worm stage (> 80 % drug effect at 50 muM), of which six revealed IC50 values between 1.8 and 5.0 muM. Except for tamoxifen citrate, all in vitro active drugs were protein kinase inhibitors. None
Limited genetic diversity of hepatitis B virus in the general population of the Offin River valley in Ghana (Publications)
countries, the other 33 formed a separate cluster distinguished by an intergroup mean distance of 1.5% from the pan-African HBV/E cluster. Successful implementation of HBV vaccination in the region was
Absence of hepatitis delta infection in a large rural HIV cohort in Tanzania (Publications)
III/IV HIV disease and median CD4 count was 179 cells/muL. The prevalence of anti-HDV positivity was 5.0% (95% confidence interval 2.8%-8.9%). There was no significant predictor of anti-HDV positivity. HDV