Causes of death and infant mortality rates among full-term births in the United States between 2010 and 2012: an observational study (Publications)
death syndrome (SIDS) (odds ratio [OR] 2.52, 95% CI 1.86, 3.42) and suffocation (OR 4.40, 95% CI 3.71, 5.21). Even though these mortality differences were partially explained by state-level differences in [...] Overall, our estimates suggest that infant mortality could be reduced by 4,003 deaths (95% CI 2,284, 5,587) annually if all states were to achieve the mortality levels of the best-performing state in each
Health in times of uncertainty in the eastern Mediterranean region, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013 (Publications)
(aged 60-80 years). The proportion of DALYs attributed to high body-mass index increased from 3.7% to 7.5% between 1990 and 2013. Burden of mental health problems and drug use increased. Most increases in DALYs [...] and Syria have resulted in a reduction in life expectancy; life expectancy in Syria would have been 5 years higher than that recorded for females and 6 years higher for males had the crisis not occurred
Fexinidazole: a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness (Publications)
and easy-to-use treatments are urgently needed. Here it is shown that fexinidazole, a 2-substituted 5-nitroimidazole rediscovered by the Drugs for Neglected Diseases initiative (DNDi) after extensive compound [...] and oral administration of fexinidazole at doses of 100 mg/kg/day for 4 days or 200 mg/kg/day for 5 days cured mice with acute and chronic infection respectively, the latter being a model for the advanced
Fexinidazole: a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness (Publications)
and easy-to-use treatments are urgently needed. Here it is shown that fexinidazole, a 2-substituted 5-nitroimidazole rediscovered by the Drugs for Neglected Diseases initiative (DNDi) after extensive compound [...] and oral administration of fexinidazole at doses of 100 mg/kg/day for 4 days or 200 mg/kg/day for 5 days cured mice with acute and chronic infection respectively, the latter being a model for the advanced
Causes of death and infant mortality rates among full-term births in the United States between 2010 and 2012: an observational study (Publications)
death syndrome (SIDS) (odds ratio [OR] 2.52, 95% CI 1.86, 3.42) and suffocation (OR 4.40, 95% CI 3.71, 5.21). Even though these mortality differences were partially explained by state-level differences in [...] Overall, our estimates suggest that infant mortality could be reduced by 4,003 deaths (95% CI 2,284, 5,587) annually if all states were to achieve the mortality levels of the best-performing state in each
Health in times of uncertainty in the eastern Mediterranean region, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013 (Publications)
(aged 60-80 years). The proportion of DALYs attributed to high body-mass index increased from 3.7% to 7.5% between 1990 and 2013. Burden of mental health problems and drug use increased. Most increases in DALYs [...] and Syria have resulted in a reduction in life expectancy; life expectancy in Syria would have been 5 years higher than that recorded for females and 6 years higher for males had the crisis not occurred
Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic... (Publications)
highest and lowest scores in 2016. In China, performance ranged from 91.5 (89.1-93.6) in Beijing to 48.0 (43.4-53.2) in Tibet (a 43.5-point difference), while India saw a 30.8-point disparity, from 64.8 (59 [...] from a high of 97.1 (95% UI 95.8-98.1) in Iceland, followed by 96.6 (94.9-97.9) in Norway and 96.1 (94.5-97.3) in the Netherlands, to values as low as 18.6 (13.1-24.4) in the Central African Republic, 19.0
Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic... (Publications)
highest and lowest scores in 2016. In China, performance ranged from 91.5 (89.1-93.6) in Beijing to 48.0 (43.4-53.2) in Tibet (a 43.5-point difference), while India saw a 30.8-point disparity, from 64.8 (59 [...] from a high of 97.1 (95% UI 95.8-98.1) in Iceland, followed by 96.6 (94.9-97.9) in Norway and 96.1 (94.5-97.3) in the Netherlands, to values as low as 18.6 (13.1-24.4) in the Central African Republic, 19.0
Bayesian spatial models applied to malaria epidemiology (Publications)
representative surveys developed by RBM that collect parasitaemia data on children below the age of 5 years and are usually carried out during high malaria transmission seasons. Historical data were extracted [...] produce spatially explicit parasitaemia risk estimates and number of infected children below the age of 5 years in Senegal. Geostatistical ZIB models were able to account for the large number of zero-prevalence [...] linked malaria survey data with Remote Sensing (RS)-derived land...
Bayesian spatial models applied to malaria epidemiology (Publications)
representative surveys developed by RBM that collect parasitaemia data on children below the age of 5 years and are usually carried out during high malaria transmission seasons. Historical data were extracted [...] produce spatially explicit parasitaemia risk estimates and number of infected children below the age of 5 years in Senegal. Geostatistical ZIB models were able to account for the large number of zero-prevalence [...] linked malaria survey data with Remote Sensing (RS)-derived land...