Ectoparasites of endemic and domestic animals in southwest Madagascar (Publications)
were also trapped in 4) villages. We identified 17 species of ectoparasites (296 individuals of ticks [5 species], 535 lice [7 spp.], 389 fleas [4 spp.] and 13 mites [1 sp.]) collected from 15 host species
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis (Publications)
proof of concept was established in an SCID mouse model of malaria, after oral administration (ED90 = 1.5 mg/kg, once a day for 4 d). Furthermore, we successfully identified an opportunity for pathogen hopping
Prenatal and postnatal medical conditions and the risk of brain tumors in children and adolescents: an international multicenter case-control study (Publications)
CT scan may be associated with the occurrence of CABTs. Cancer Epidemiol Biomarkers Prev; 26(1); 110-5. (c)2016 AACR.
Anti-inflammatory and quinone reductase-inducing compounds from <em>Beilschmiedia mannii</em> (Publications)
1: and 2: were the most active. The concentrations to double the quinone reductase activity were 7.5 microM for compound 1: and 6.1 microM for compound 2: . Compounds 1: and 2: inhibited nuclear factor-kappa
Life cycle maintenance and drug-sensitivity assays for early drug discovery in <em>Schistosoma mansoni</em> (Publications)
along the drug-screening cascade are also described. In these assays, which can be performed within 5 d, the effect of a drug is determined by phenotypic assessment of the parasites' viability and morphology
Discovery and characterization of <em>Mycobacterium basiliense</em> sp. nov., a nontuberculous <em>Mycobacterium </em>isolated from human lungs (Publications)
genome sequence was obtained through combining short and long-read sequencing, providing a genome of 5.6 Mb. The genome appears to be highly intact, syntenic with that of M. marinum, with very few insertion
Diagnostic performance of conventional and ultrasensitive rapid diagnostic tests for malaria in febrile outpatients in Tanzania (Publications)
us-qPCR (Npos=357) only marginally (us-RDT, 75%; co-RDT, 73%). Specificity of both RDTs was > 99%. 5 of 11 additional positive us-RDT were negative in us-qPCR. HRP2 concentration was above the detectable
Multistage antiplasmodium activity of astemizole analogues and inhibition of hemozoin formation as a contributor to their mode of action (Publications)
first ever gametocytes screening of AST and its analogues revealed their moderate activity (IC50: 1 - 5 microM) against late stage P. falciparum gametocytes, while the evaluation of activity against P. berghei
The epidemiology of multiple <em>Plasmodium falciparum</em> infections. 8. Effect of iron supplementation and malaria prophylaxis in infants on... (Publications)
under conditions of intense transmission, all samples of P. falciparum obtained from children aged 5 and 8 months were genotyped by polymerase chain reaction-restriction fragment length polymorphism analysis
Air quality in Tehran, Iran: Evaluating acute health effects and modeling the long-term spatial variability (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/air-quality-in-tehran-iran-evaluating-acute-health-effects-and-modeling-the-long-term-spatial-variability
effects of the air quality index, constructed of daily air quality data of a set of pollutants (PM10, PM2.5, SO2, NO2, O3, and CO). The vision is to translate the daily air quality into daily burden of death