Spatial and sector-specific contributions of emissions to ambient air pollution and mortality in European cities: a health impact assessment (Publications)
by industry (13·8% [6·0]), transport (13·5% [5·8]), energy (10·0% [6·4]), and shipping (5·5% [5·7]). For NO2, the main contributor to mortality was transport (48·5% [SD 15·2]), with additional contributions [...] energy (14·7% [12·9]), residential (10·3% [5·0]), and shipping (9·7% [12·7]). The mean city contribution to its own air pollution mortality was 13·5% (SD 9·9) for PM2·5 and 34·4% (19·6) for NO2, and contribution [...] increased among cities of largest area (22·3% [12·2] for PM2·5 and...
Geographical variations of the associations between health interventions and all-cause under-five mortality in Uganda (Publications)
in U5M. In Kampala and Mid-Eastern, IPTp had the largest associated with U5M. In Central1 and East-Central, oral rehydration solution and postnatal care were associated with highest decreases in U5M re [...] associations of interventions with U5M rate at national and sub-national scales in Uganda and to identify interventions associated with the largest reductions in U5M rate at the sub-national scale. METHODS: [...] associations between all-cause U5M and interventions at national and regional...
Mortality attributable to ambient fine particulate matter and nitrogen dioxide in Switzerland in 2019: use of two-pollutant effect estimates (Publications)
058] per 10 mug/m(3) NO(2) adjusted for PM(2.5)), we found 1977 deaths (19,071 years of life lost) attributable to PM(2.5) and NO(2) together (23% from PM(2.5)). Deaths using alternative effect estimates [...] Estimated premature mortality attributable to PM(2.5) alone was higher than to both PM(2.5) and NO(2) combined. Furthermore, the proportion of deaths from PM(2.5) was lower than from NO(2) in the two-pollutant [...] estimating the adult mortality in Switzerland in 2019 attributable to...
Mortality attributable to ambient fine particulate matter and nitrogen dioxide in Switzerland in 2019: use of two-pollutant effect estimates (Publications)
058] per 10 mug/m(3) NO(2) adjusted for PM(2.5)), we found 1977 deaths (19,071 years of life lost) attributable to PM(2.5) and NO(2) together (23% from PM(2.5)). Deaths using alternative effect estimates [...] Estimated premature mortality attributable to PM(2.5) alone was higher than to both PM(2.5) and NO(2) combined. Furthermore, the proportion of deaths from PM(2.5) was lower than from NO(2) in the two-pollutant [...] estimating the adult mortality in Switzerland in 2019 attributable to...
Geographical variations of the associations between health interventions and all-cause under-five mortality in Uganda (Publications)
in U5M. In Kampala and Mid-Eastern, IPTp had the largest associated with U5M. In Central1 and East-Central, oral rehydration solution and postnatal care were associated with highest decreases in U5M re [...] associations of interventions with U5M rate at national and sub-national scales in Uganda and to identify interventions associated with the largest reductions in U5M rate at the sub-national scale. METHODS: [...] associations between all-cause U5M and interventions at national and regional...
Air pollution and atherosclerosis: a cross-sectional analysis of four European cohort studies in the ESCAPE study (Publications)
72% (95% Confidence Interval [CI]: -0.65%, 2.10%) per 5 microg/m3 increase in PM2.5 and 0.42% (95% CI: -0.46%, 1.30%) per 10-5/m increase in PM2.5abs. Living in proximity to high traffic was also positively [...] al marker of atherosclerosis. METHODS: Individually assigned levels of NO2, NOx, PM2.5, absorbance of PM2.5 (PM2.5abs), PM10, PMcoarse, and two indicators of residential proximity to highly trafficked [...] extended meta-analysis for PM2.5 with three other previously published studies,...
Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers' children against airway inflammation and colitis (Publications)
as the sialic acid N-glycolylneuraminic acid (Neu5Gc), might play a significant role. METHODS: Exposure to Neu5Gc was evaluated by quantifying anti-Neu5Gc antibody levels in sera of children enrolled in [...] 4.5 years [n = 700], and 6 years [n = 728]), and we associated them with asthma and wheeze. The effect of Neu5Gc was examined in murine airway inflammation and colitis models, and the role of Neu5Gc in [...] in nonatopic subjects. Exposure to Neu5Gc in mice resulted in reduced airway...
Ambient air pollution and atherosclerosis in Los Angeles (Publications)
ions of ambient PM2.5. Exposure values were assigned from a PM2.5 surface derived from a geostatistical model. Individually assigned annual mean PM2.5 concentrations ranged from 5.2 to 26.9 microg/m3 (mean [...] association between atherosclerosis and long-term exposure to ambient PM up to 2.5 microm in aerodynamic diameter (PM2.5). Baseline data included assessment of the carotid intima-media thickness (CIMT) [...] (mean, 20.3). For a cross-sectional exposure contrast of 10 microg/m3 PM2.5,...
Ambient air pollution and atherosclerosis in Los Angeles (Publications)
ions of ambient PM2.5. Exposure values were assigned from a PM2.5 surface derived from a geostatistical model. Individually assigned annual mean PM2.5 concentrations ranged from 5.2 to 26.9 microg/m3 (mean [...] association between atherosclerosis and long-term exposure to ambient PM up to 2.5 microm in aerodynamic diameter (PM2.5). Baseline data included assessment of the carotid intima-media thickness (CIMT) [...] (mean, 20.3). For a cross-sectional exposure contrast of 10 microg/m3 PM2.5,...
Air pollution and atherosclerosis: a cross-sectional analysis of four European cohort studies in the ESCAPE study (Publications)
72% (95% Confidence Interval [CI]: -0.65%, 2.10%) per 5 microg/m3 increase in PM2.5 and 0.42% (95% CI: -0.46%, 1.30%) per 10-5/m increase in PM2.5abs. Living in proximity to high traffic was also positively [...] al marker of atherosclerosis. METHODS: Individually assigned levels of NO2, NOx, PM2.5, absorbance of PM2.5 (PM2.5abs), PM10, PMcoarse, and two indicators of residential proximity to highly trafficked [...] extended meta-analysis for PM2.5 with three other previously published studies,...