Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global... (Publications)
attributed to kidney dysfunction was 296 632 (95% uncertainty interval: 249 965-343 962), which was about 2.5 times higher than in the year 1990. Afghanistan, Egypt, and Saudi Arabia had the highest, and Kuwait
Clonal expansion of artemisinin-resistant <em>Plasmodium falciparum</em> in Uganda is associated with substandard treatment practices (Publications)
was more frequently observed in patients sampled 28-days after RAS treatment (OR = 3.9, 95% CI 1.7, 9.5, p= 0.002) of whom 44% were treated with an artemisinin monotherapy. Parasite editing and phenotyping
Seroprevalence trends of anti-SARS-CoV-2 antibodies and associated risk factors: a population-based study (Publications)
from 11 Swiss cantons. Seroprevalence was 3.7% (95% CI 2.1-4.9) in period 1, 16.2% (95% CI 14.4-17.5) in period 2, and 72.0% (95% CI 70.3-73.8) in period 3, with regional variations. In period 1, younger
Prenatal depression severity and postpartum care utilization in a medicaid population (Publications)
Results: The majority (64.2%) of women received a mild/moderate prenatal depression diagnosis and 52.5% of the total sample attended their postpartum care visit. After adjusting for confounders, we found
Population pharmacokinetics and clinical response for artemether-lumefantrine in pregnant and nonpregnant women with uncomplicated <em>Plasmodium... (Publications)
nonpregnant patients. The overall PCR-uncorrected treatment failure rates were 18% in pregnant women and 5% in nonpregnant women (odds ratio [OR] = 4.04; P value of 0.22). A high median day 7 lumefantrine c
A <em>Plasmodium falciparum</em> PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surface (Publications)
Here, we show that PHIST member PFE1605w binds the PfEMP1 intracellular segment directly with Kd = 5 +/- 0.6 muM, comigrates with PfEMP1 during export, and locates in knobs. PHIST variants that do not
A tradition and an epidemic: determinants of the campylobacteriosis winter peak in Switzerland (Publications)
consumers revealed chicken as the type of meat with the highest risk of disease (mOR 3.8, 95 % CI 1.1-13.5). Most frequently reported signs and symptoms among patients were diarrhoea (98 %), abdominal pain (81
Rice irrigation and schistosomiasis in savannah and forest areas of Côte d'Ivoire (Publications)
S. haematobium prevalence was 0.9%, 4.4% and 1.7% and S. mansoni prevalence was 61.3%, 46.6% and 17.5% in R2, in R1 and R0, respectively. Prevalences of S. mansoni adjusted for village effects were sig
Anti-trypanosomatid elemanolide sesquiterpene lactones from<em> Vernonia lasiopus </em>O. Hoffm (Publications)
microg/mL against T.b. rhodesiense trypomastigotes. This compound showed a selectivity index of 14.5, which makes it an interesting candidate for in vivo tests and determination of its mechanism of action
Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa (Publications)
average of 4.9 years for 50% of seroconverters to be linked to care (95% confidence intervals (CI): 4.2-5.7). Among all cohort members that were linked to care, the median CD4 count at linkage was 350 cells/muL
