The epidemiology of chronic kidney disease and the association with non-communicable and communicable disorders in a population of sub-Saharan Africa (Publications)
History of tuberculosis (OR 3.75, 95% CI 1.66-8.18; p = 0.001) and schistosomiasis (OR 2.49, 95% CI 1.13-5.18; p = 0.02) were associated with CKD. A trend was seen for increasing systolic blood pressure (OR
Importance of routine viral load monitoring: higher levels of resistance at ART failure in Uganda and Lesotho compared with Switzerland (Publications)
virological failure (n = 61) was selected. Results: We found that 50.8% of individuals in the SHCS, 72.5% in Uganda and 81.0% in Lesotho harboured HIV with high-level resistance to at least two drugs from
Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort (Publications)
asthma was higher in women than in men throughout all the reproductive years (HR 3.51; 95% CI 2.21 to 5.58), whereas no gender difference was observed for the incidence of allergic asthma.ConclusionsThis
HMOX1 and GST variants modify attenuation of FEF25-75% decline due to PM10 reduction (Publications)
alleles or the GSTP1 Val/Val genotype profited significantly more from a 10 microg.m(-3) reduction (26.5 mL.s(-1) and 27.3 mL.s(-1) respectively) than non-carriers. Benefits of a reduction in PM(10) exposure
Infectious diseases are associated with carotid intima media thickness in adolescence (Publications)
diseases (p = 0.136). Two-thirds were vaccinated according to recommendations (boys 56%, girls 61.5%, p = 0.567). Sex-stratified analyses yielded significantly increased CIMT in boys with > /=3 infectious
Early life origins of lung ageing: early life exposures and lung function decline in adulthood in two European cohorts aged 28-73 years (Publications)
[-3.85;-1.38]). Less rapid FEV1-decline was found in subjects who had attended daycare (3.98ml [2.78;5.18]), and indicated in subjects with pets in childhood (0.97ml [-0.16;2.09]). High maternal age and
Latent class analysis reveals clinically relevant atopy phenotypes in two birth cohorts (Publications)
children without an established asthma diagnosis. Severe atopy was associated with an elevated interleukin-5/interferon-gamma ratio. A path analysis among sensitized children revealed that among all features of
Effects of radon and UV exposure on skin cancer mortality in Switzerland (Publications)
neighborhood socioeconomic position, and UV exposure from outdoor occupation. RESULTS: The study included 5.2 million adults (mean age 48 y) and 2,989 skin cancer deaths, with 1,900 indicating malignant melanoma
Evaluation of the novel substrate RUG™ for the detection of<em> Escherichia coli</em> in water from temperate (Zurich, Switzerland) and tropical... (Publications)
m-ColiBlue24®. In temperate waters, AT-RUG was found to be as sensitive as m-TEC (97.0%) and C-18 (98.5%) and showed strong agreement with the reference methods. The false-positive rate for E. coli detection
Prospective European-wide multicentre study on a blood based real-time PCR for the diagnosis of acute schistosomiasis (Publications)
schistosomiasis endemic regions and freshwater contacts, an episode of fever (body temperature > /=38.5 degrees C) and an absolute or relative eosinophil count of > /=700/mul or 10%, were eligible for pa