Cross-validation of bioelectrical impedance analysis for the assessment of body composition in a representative sample of 6- to 13-year-old children (Publications)
measured with DXA. Body resistance (R) was measured at 50 kHz with 4-BIA and segmental body resistance at 5, 50, 250 and 500 kHz with 8-BIA. The resistance index (RI) was calculated as height(2)/R. Selection
A tradition and an epidemic: determinants of the campylobacteriosis winter peak in Switzerland (Publications)
consumers revealed chicken as the type of meat with the highest risk of disease (mOR 3.8, 95 % CI 1.1-13.5). Most frequently reported signs and symptoms among patients were diarrhoea (98 %), abdominal pain (81
A <em>Plasmodium falciparum</em> PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surface (Publications)
Here, we show that PHIST member PFE1605w binds the PfEMP1 intracellular segment directly with Kd = 5 +/- 0.6 muM, comigrates with PfEMP1 during export, and locates in knobs. PHIST variants that do not
Population pharmacokinetics and clinical response for artemether-lumefantrine in pregnant and nonpregnant women with uncomplicated <em>Plasmodium... (Publications)
nonpregnant patients. The overall PCR-uncorrected treatment failure rates were 18% in pregnant women and 5% in nonpregnant women (odds ratio [OR] = 4.04; P value of 0.22). A high median day 7 lumefantrine c
Infectious diseases are associated with carotid intima media thickness in adolescence (Publications)
diseases (p = 0.136). Two-thirds were vaccinated according to recommendations (boys 56%, girls 61.5%, p = 0.567). Sex-stratified analyses yielded significantly increased CIMT in boys with > /=3 infectious
Efficacy and safety of praziquantel against light infections of <em>Opisthorchis viverrini</em>: a randomised parallel single blind dose-ranging trial (Publications)
observed dose range. We observed cure rates ranging from 92.7-93.3% and egg reduction rates above 99.5% for all praziquantel-treatment groups. Adverse events were mild but higher in the standard treatment
Latent class analysis reveals clinically relevant atopy phenotypes in two birth cohorts (Publications)
children without an established asthma diagnosis. Severe atopy was associated with an elevated interleukin-5/interferon-gamma ratio. A path analysis among sensitized children revealed that among all features of
Effects of radon and UV exposure on skin cancer mortality in Switzerland (Publications)
neighborhood socioeconomic position, and UV exposure from outdoor occupation. RESULTS: The study included 5.2 million adults (mean age 48 y) and 2,989 skin cancer deaths, with 1,900 indicating malignant melanoma
Early life origins of lung ageing: early life exposures and lung function decline in adulthood in two European cohorts aged 28-73 years (Publications)
[-3.85;-1.38]). Less rapid FEV1-decline was found in subjects who had attended daycare (3.98ml [2.78;5.18]), and indicated in subjects with pets in childhood (0.97ml [-0.16;2.09]). High maternal age and
HMOX1 and GST variants modify attenuation of FEF25-75% decline due to PM10 reduction (Publications)
alleles or the GSTP1 Val/Val genotype profited significantly more from a 10 microg.m(-3) reduction (26.5 mL.s(-1) and 27.3 mL.s(-1) respectively) than non-carriers. Benefits of a reduction in PM(10) exposure