Evaluation of emodepside in laboratory models of human intestinal nematode and schistosome infections (Publications)
confirmed in vivo. Hamsters infected with the hookworms were cured when administered orally with 2.5 mg/kg of the drug. Emodepside was also highly active in vivo against T. muris (ED50 = 1.2 mg/kg). Emodepside
Mortality of neurological disorders in Tanzania: analysis of baseline data from sample vital registration with verbal autopsy (SAVVY) (Publications)
06% (95% CI: 1.12-3.01). Overall, mortality of ND was estimated with a CSMF of 4.99% (95% CI: 4.40-5.58). Conclusions: The SAVVY survey provides estimates of mortality burden of ND in Tanzania. The study
Preparation of sesquiterpene lactone-loaded PLA nanoparticles and evaluation of their antitrypanosomal activity (Publications)
a rounded knotty depression like a navel orange. The average particle sizes were 202.3, 220.3, 219.5, 216.9, and 226.4 nm for alpha-santonin, arglabin, schkuhrin II, vernolepin, and eucannabinolide, r
Effect of multidimensional lifestyle intervention on fitness and adiposity in predominantly migrant preschool children (Ballabeina): cluster... (Publications)
of the 727 preschool children had informed consent and were present for baseline measures (mean age 5.1 years (SD 0.7), 72% migrants of multicultural origins). No children withdrew, but 26 moved away.
The treatment of non-malarial febrile illness in Papua New Guinea: findings from cross sectional and longitudinal studies of health worker practice (Publications)
respectively), some form of antibiotic (72.7 & 73.4%, respectively) and/or an anthelminthic (17.9 & 16.5%, respectively). Prescribing behaviour was adherent with the recommendations in the standard treatment
Timing of antenatal care for adolescent and adult pregnant women in south-eastern Tanzania (Publications)
analysis. RESULTS: The majority of pregnant women initiated antenatal care attendance with an average of 5 gestational months. Belonging to the Sukuma ethnic group compared to other ethnic groups such as the
Fine-scale spatial and temporal heterogeneities in insecticide resistance profiles of the malaria vector,<em> Anopheles arabiensis</em> in rural... (Publications)
0.75% permethrin, 4% DDT, 4% dieldrin, 0.1% bendiocarb, 0.1% propoxur, 0.25% pirimiphos-methyl and 5% malathion. A hydrolysis probe assay was used to screen for L1014F ( kdr-w) and L1014S ( kdr-e) mutations
Comparison of novel and standard diagnostic tools for the detection of<em> Schistosoma mekongi</em> infection in Lao People's Democratic Republic and... (Publications)
viverrini, hookworm, Trichuris trichiura, Ascaris lumbricoides and Taenia spp. were 50.4%, 28.1%, 3.5%, 0.3% and 1.9%, respectively. In the urine samples, the tests for CCA and CAA detected S. mekongi
HIV viral load as an independent risk factor for tuberculosis in South Africa: collaborative analysis of cohort studies (Publications)
We included 44,260 patients with a median follow-up time of 2.7 years (interquartile range [IQR] 1.0-5.0); 3,819 incident TB cases were recorded (8.6%). At baseline, the median age was 34 years (IQR 28-41);
Impact of geocoding methods on associations between long-term exposure to urban air pollution and lung function (Publications)
decreased when other geocoding approaches were used (i.e. for FVC% predicted -2.81 (95% CI: -0.26, -5.35) using NavTEQ or 2.08 (95%CI -4.63, 0.47, p=0.11) using Google Maps). CONCLUSIONS: Our findings suggest