Long-term exposure to air pollution and mortality from dementia, psychiatric disorders, and suicide in a large pooled European cohort: ELAPSE study (Publications)
interval [CI]: 1.13, 1.70 per 10 microg/m(3)), PM2.5 (HR = 1.29; 95 % CI: 0.98, 1.71 per 5 microg/m(3)), and BC (HR = 1.37; 95 % CI: 1.11, 1.69 per 0.5 x 10(-5)/m) with psychiatric disorders mortality, as well [...] residential addresses, annual mean levels of fine particulate matter (PM2.5), nitrogen dioxide (NO2), black carbon (BC), ozone (O3), and 8 PM2.5 components were estimated using Europe-wide hybrid land-use regression [...] 1.38]; PM2.5: HR = 1.19 [95 % CI: 0.76, 1.87]; BC: HR = 1.08...
Heat-related cardiorespiratory mortality: effect modification by air pollution across 482 cities from 24 countries (Publications)
and 14.3% (95% CI 14.1-14.5) at low, medium, and high levels of PM2.5, respectively. Similarly, cardiovascular mortality increased by 1.6 (95%CI 1.5-1.6), 5.1 (95%CI 5.1-5.2), and 8.7 (95%CI 8.7-8.8) [...] Location-specific daily death counts and exposure data (e.g., particulate matter with diameters ≤ 2.5 µm [PM2.5]) were obtained from 2000 to 2018. We used location-specific confounder-adjusted Quasi-Poisson [...] pollutant. We extracted heat effects at low, medium, and high levels of...
Development and evaluation of a personal particulate organic and mass sampler (Publications)
outdoor site, and in residences. Daily particulate mass concentrations averaged 10.0 +/- 5.2, 12.0 +/- 5.3, and 11.2 +/- 5.1 microg m(-3) for the Federal Reference Method, the Harvard Personal Exposure Monitor [...] a series of PM2.5 indoor organic carbon (OC) measurements from single quartz filters, the apparent indoor OC averaged 7.7 +/- 0.8 microg of C m(-3), which was close to the indoor PM2.5 mass from collocated [...] developed to meet these criteria. The PPOMS uses activated...
Reducing ambient levels of fine particulates could substantially improve health: a mortality impact assessment for 26 European cities (Publications)
that could be prevented by reducing PM(2.5) annual levels to 25 microg/m3, 20 microg/m3, 15 microg/m3 and 10 microg/m3 in 26 European cities. The various PM(2.5) concentrations were chosen as different [...] derived from the paper by Pope et al (2002). If no direct PM(2.5 )measurements were available, then the PM(10) measurements were converted to PM(2.5 )using a local or an assumed European conversion factor. We [...] conversion factor for PM(2.5). Specifically, using the "at least" approach,...
Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: pooled analysis (Publications)
observed. Higher exposure to PM2.5, nitrogen dioxide, and black carbon was associated with significantly increased risk of almost all outcomes. An increase of 5 microg/m(3) in PM2.5 was associated with 13% (95% [...] (PM2.5), nitrogen dioxide, ozone, and black carbon. MAIN OUTCOME MEASURES: Deaths due to natural causes and cause specific mortality. RESULTS: Of 325 367 adults followed-up for an average of 19.5 years [...] confidence interval 10.6% to 15.5%) increase in natural deaths; the...
Coarse particulate air pollution and daily mortality: a global study in 205 cities (Publications)
ambient coarse particulate matter (PM2.5-10) and daily mortality is not fully understood at a global scale. OBJECTIVES: To evaluate the short-term associations between PM2.5-10 and total, cardiovascular, and [...] exposure to ambient PM2.5-10 and total, cardiovascular and respiratory mortality, suggesting the need to establish a unique guideline or regulatory limit for daily concentrations of PM2.5-10. [...] respiratory) and air pollution data from 205 cities in 20 countries/regions....
Long-term exposure to ambient air pollution and incidence of cerebrovascular events: results from 11 European cohorts within the ESCAPE project (Publications)
(ESCAPE). The exposures were: PM2.5 (particulate matter [PM] below 2.5 microm in diameter), coarse PM (PM between 2.5 and 10 microm), PM10 (PM below 10 microm), PM2.5 absorbance, nitrogen oxides, and two [...] estimation. RESULTS: 99,446 subjects were included, 3,086 of whom developed stroke. A 5-mug/m3 increase in annual PM2.5 exposure was associated with 19% increased risk of incident stroke (hazard ratio [HR] [...] association with PM2.5 was apparent among those aged 60+ years (HR = 1.40, 95%...
Outdoor air pollution and the burden of childhood asthma across Europe (Publications)
m(-3). PM2.5 ranged from 2.0 to 41.1 microg.m(-3), with a mean of 11.6 microg.m(-3). BC ranged from 0.003 to 3.7x10(-5)m(-1), with a mean of 1.0x10(-5)m(-1). Compliance with the NO2 and PM2.5 WHO guidelines [...] (11%) incident cases. Meeting the minimum air pollution levels for NO2 (1.5 microg.m(-3)), PM2.5 (0.4 microg.m(-3)) and BC (0.4x10(-5)m(-1)), respectively, was estimated to prevent 135 257 (23%), 191 883 (33%) [...] We estimated the burden of incident childhood asthma that may be...
Pulmonary effects of indoor- and outdoor-generated particles in children with asthma (Publications)
associated with an increase in eNO (Eag: 5.0 ppb per 10-microg/m3 increase in PM2.5; 95% CI, 0.3 to 9.7; p = 0.04; Eig: 3.3 ppb per 10-microg/m3 increase in PM2.5; 95% CI, -1.1 to 7.7; p = 0.15). Effects [...] for estimating infiltration efficiency to separate personal exposure (E) to PM2.5 (PM with aerodynamic diameter < or = 2.5 microm) into its indoor-generated (Eig) and ambient-generated (Eag) components [...] sample size of eight children, Eag was marginally associated with increases in eNO...
Long-term exposure to ambient air pollution and incidence of cerebrovascular events: results from 11 European cohorts within the ESCAPE project (Publications)
(ESCAPE). The exposures were: PM2.5 (particulate matter [PM] below 2.5 microm in diameter), coarse PM (PM between 2.5 and 10 microm), PM10 (PM below 10 microm), PM2.5 absorbance, nitrogen oxides, and two [...] estimation. RESULTS: 99,446 subjects were included, 3,086 of whom developed stroke. A 5-mug/m3 increase in annual PM2.5 exposure was associated with 19% increased risk of incident stroke (hazard ratio [HR] [...] association with PM2.5 was apparent among those aged 60+ years (HR = 1.40, 95%...