Fexinidazole (Page)
https://www.swisstph.ch/fr/about/med/clinical-operations/fexinidazole
e products for the treatment of this fatal disease. One promising agent is Fexinidazole. It is a 2-5-nitroimidazole, formulated for oral administration, which has been shown to possess in vitro and in
Our Expertise in Long-Term Studies (Page)
https://www.swisstph.ch/fr/about/support-us/emerging-health-risks/expertise-in-long-term-studies
health data in biobanks The state-of-the-art biobanks at our new headquarters allow for the storage of 1.5 million biological samples from study participants. The health data stored in biobanks enables us to
Advances with the Chinese anthelminthic drug tribendimidine in clinical trials and laboratory investigations (Publications)
school-aged children using a rigorous diagnostic approach found a cure rate against hookworm of 76.5%. A single oral dose of tribendimidine showed only low cure rates against Trichuris trichiura (23.9-36
Prévalences et polyparasitisme des protozoaires intestinaux et répartition spatiale d'<em>Entamoeba histolytica</em>/<em>Entamoeba dispar</em> et... (Publications)
were Endolimax nanus (83.8%) and E. coli (74.7%). The regional prevalence of G. intestinalis was 17.5% and of E. histolytica/E. dispar 11.3%. Both species were found in each of the 57 schools. The prevalence
Influence of MMR-vaccinations and diseases on atopic sensitization and allergic symptoms in Swiss schoolchildren (Publications)
(GMT) lU/ml (95% Cl) 2.8 (2.0-3.9) vs. 1.2 (1.0-1.4), mumps: GMT PE/ml (95% Cl) 16.3 (13.9-19.1) vs. 8.5 (6.1-11.7). With respect to atopic sensitization similar associations for exposure by natural MMR-infections
Aromatase and breast cancer susceptibility (Publications)
that would predict its functional relevance. We describe a newly identified TTC deletion in intron 5 of the CYP19 gene that is associated with the (TTTA)n repeat polymorphism. Neither this polymorphism
Comparison of community-wide, integrated mass drug administration strategies for schistosomiasis and soil-transmitted helminthiasis: a... (Publications)
BACKGROUND: More than 1·5 billion people are affected by schistosomiasis or soil-transmitted helminthiasis. WHO's recommendations for mass drug administration (MDA) against these parasitic infections emphasise
A nationwide survey of the quality of antimalarials in retail outlets in Tanzania (Publications)
quantification analysis. Quality of amodiaquine drugs was relatively better but still unacceptable as 7.5% did not comply within the tolerance limits of the dissolution analysis. Formulations of the artemisinin
Mosquito net coverage in years between mass distributions: a case study of Tanzania, 2013 (Publications)
80% through the addition of UTNs. Overall net use of the population was low (LLINs: 32.8%; UTNs: 9.5%) and net use:access ratio was below target level (LLINs: 0.66; UTN: 0.50). Both measures varied si
Efficacy and safety of tribendimidine versus praziquantel against <em>Opisthorchis viverrini</em> in Laos: an open-label, randomised, non-inferiority,... (Publications)
intensity and were more frequent in the praziquantel group than in the tribendimidine group (odds ratio 4.5, 95% CI 3.2-6.3; p