Two-year impact of community-based health screening and parenting groups on child development in Zambia: follow-up to a cluster-randomized controlled... (Publications)
o-treat analysis was performed for primary outcomes measured at the year 2 follow-up: stunting and 5 domains of neurocognitive development measured using the Bayley Scales of Infant and Toddler Develo
Identification of risk factors for rabies exposure and access to post-exposure prophylaxis in Chad (Publications)
non-compliance observed in rural areas. Access to vaccine before the study was alarmingly low, with only 8.5% accessing PEP. Despite facilitated collaboration between human health and veterinary services through
Characterization of novel antimalarial compound ACT-451840: preclinical assessment of activity and dose-efficacy modeling (Publications)
potently prevented male gamete formation from the gametocyte stage with a 50% inhibition concentration of 5.89 nM (SD: +/- 1.80 nM) and dose-dependently blocked oocyst development in the mosquito with a 50%
Gametocyte carriage in uncomplicated <em>Plasmodium falciparum</em> malaria following treatment with artemisinin combination therapy: a systematic... (Publications)
(adjusted odds ratio (AOR), 9.05; 95 % CI, 3.74-21.90; P < 0.001) and new (AOR, 3.03; 95 % CI, 1.66-5.54; P < 0.001) infections with asexual-stage parasites were strongly associated with development of
Assessing and managing wounds of Buruli ulcer patients at the primary and secondary health care levels in Ghana (Publications)
compared to 40% at the SHC center, where the majority required split-skin grafting (75%) or excision (12.5%). Only 9% of wounds at the PHC center, but 50% at the SHC center were complicated by bacterial infection
Digital support systems to improve child health and development in Peru: protocol for a randomized controlled trial (Publications)
through the digital platform. The primary study outcome is children's overall development at the age of 2.5 years, using the internationally validated long form of the Global Scales for Early Development. Secondary
Aminoindoles, a novel scaffold with potent activity against <em>Plasmodium falciparum</em> (Publications)
However, parasites recrudesced by day 9. Dosing at 200 mg/kg/day twice a day resulted in cures of 3/5 animals. The compound had comparable activity against P. falciparum blood stages in a human-engrafted
Blockchain high coverage rabies post-exposure prophylaxis to achieve zero human rabies deaths in Africa (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/blockchain-high-coverage-rabies-post-exposure-prophylaxis-to-achieve-zero-human-rabies-deaths-in-africa
rabies diagnostic tests adapted to African settings to inform and accelerate therapeutic decisions. 5) To ensure the validity of the approach, by monitoring patient compliance with ID-PEP, clinical outcome
Low quality of routine microscopy for malaria at different levels of the health system in Dar es Salaam (Publications)
Over-diagnosis was massive, with many false positive results reported as very low parasitaemia (1 to 5 parasites per 200 WBC). RDTs should replace microscopy as first-line diagnostic tool for malaria in