Cancer risk assessment of selected hazardous air pollutants in Seattle (Publications)
cancer risk was 6.09 x 10(-5), with the background (1.61 x 10(-5)), diesel (9.82 x 10(-6)) and wood burning (9.45 x 10(-6)) sources being the primary risk sources. The PM(2.5) mass concentration contributed [...] lifetime excess cancer risks of selected hazardous air pollutants. We analyzed the speciated PM(2.5) and VOCs data collected at the Beacon Hill in Seattle, WA between 2000 and 2004 with the Multilinear [...] contributed 20% of the total risk. The 5th percentile of the risk estimates of...
A household-based community health worker programme for non-communicable disease, malnutrition, tuberculosis, HIV and maternal health: a stepped-wedge... (Publications)
interval: -2.5 to 0.5)) while maintaining the already low default rates for HIV patients (0.0 pp, 95% CI: -0.6 to 0.5). First trimester ANC attendance increased by approximately 30% (6.5pp (-0.3, 15.8)) [...] facilities. The intervention roll-out was staggered every 3 months over 18 months, with CHWs receiving a 5-day foundational training for their new tasks and assigned 20-40 households for monthly (or more frequent) [...] 8)) and paediatric malnutrition case finding declined by 10% (-0.6 per...
Health impact and related cost of ambient air pollution in Tehran (Publications)
economic impact associated with these health effects. Using PM2.5 data from ground-level air pollution measurements in Tehran, we estimated PM2.5 exposure for 349 neighborhoods in Tehran, by the Environmental [...] tal Benefits Mapping and Analysis Program (BenMAP-CE). We considered five scenarios related to PM2.5 levels: an increase to 35mug/m(3); a reduction to 25mug/m(3); a reduction to 15mug/m(3); a reduction [...] guideline value); and a full roll-back, assuming a reduction to 2.4mug/m(3)....
Long-term exposure to particulate matter constituents and the incidence of coronary events in 11 European cohorts (Publications)
analysis. 5,157 incident coronary events were identified within 100,166 persons followed on average for 11.5 years. Long-term residential concentrations of PM < 10 mum (PM10), PM < 2.5 mum (PM2.5), and a [...] increase in PM2.5 K were associated with a 6% (hazard ratio and 95% confidence interval: 1.06 [1.01, 1.12]) and 18% (1.18 [1.06, 1.32]) increase in coronary events. Estimates for PM10 Si and PM2.5 Fe were also
A var gene upstream element controls protein synthesis at the level of translation initiation in <em>Plasmodium falciparum</em> (Publications)
control has recently been identified for the var2csa gene, where an mRNA element in the 5' untranslated region (5' UTR) is involved in the reversible inhibition of translation of var2csa transcripts. Here [...] var gene regulation to the common upsC type. We identified a 5' UTR sequence that inhibits translation of upsC-derived mRNAs. Importantly, this 5' UTR element efficiently inhibits translation even in the [...] epigenetic silencing. Singular gene choice is controlled at the level of...
A household-based community health worker programme for non-communicable disease, malnutrition, tuberculosis, HIV and maternal health: a stepped-wedge... (Publications)
interval: -2.5 to 0.5)) while maintaining the already low default rates for HIV patients (0.0 pp, 95% CI: -0.6 to 0.5). First trimester ANC attendance increased by approximately 30% (6.5pp (-0.3, 15.8)) [...] facilities. The intervention roll-out was staggered every 3 months over 18 months, with CHWs receiving a 5-day foundational training for their new tasks and assigned 20-40 households for monthly (or more frequent) [...] 8)) and paediatric malnutrition case finding declined by 10% (-0.6 per...
A var gene upstream element controls protein synthesis at the level of translation initiation in <em>Plasmodium falciparum</em> (Publications)
control has recently been identified for the var2csa gene, where an mRNA element in the 5' untranslated region (5' UTR) is involved in the reversible inhibition of translation of var2csa transcripts. Here [...] var gene regulation to the common upsC type. We identified a 5' UTR sequence that inhibits translation of upsC-derived mRNAs. Importantly, this 5' UTR element efficiently inhibits translation even in the [...] epigenetic silencing. Singular gene choice is controlled at the level of...
Long-term exposure to particulate matter constituents and the incidence of coronary events in 11 European cohorts (Publications)
analysis. 5,157 incident coronary events were identified within 100,166 persons followed on average for 11.5 years. Long-term residential concentrations of PM < 10 mum (PM10), PM < 2.5 mum (PM2.5), and a [...] increase in PM2.5 K were associated with a 6% (hazard ratio and 95% confidence interval: 1.06 [1.01, 1.12]) and 18% (1.18 [1.06, 1.32]) increase in coronary events. Estimates for PM10 Si and PM2.5 Fe were also
Health impact and related cost of ambient air pollution in Tehran (Publications)
economic impact associated with these health effects. Using PM2.5 data from ground-level air pollution measurements in Tehran, we estimated PM2.5 exposure for 349 neighborhoods in Tehran, by the Environmental [...] tal Benefits Mapping and Analysis Program (BenMAP-CE). We considered five scenarios related to PM2.5 levels: an increase to 35mug/m(3); a reduction to 25mug/m(3); a reduction to 15mug/m(3); a reduction [...] guideline value); and a full roll-back, assuming a reduction to 2.4mug/m(3)....
Cancer risk assessment of selected hazardous air pollutants in Seattle (Publications)
cancer risk was 6.09 x 10(-5), with the background (1.61 x 10(-5)), diesel (9.82 x 10(-6)) and wood burning (9.45 x 10(-6)) sources being the primary risk sources. The PM(2.5) mass concentration contributed [...] lifetime excess cancer risks of selected hazardous air pollutants. We analyzed the speciated PM(2.5) and VOCs data collected at the Beacon Hill in Seattle, WA between 2000 and 2004 with the Multilinear [...] contributed 20% of the total risk. The 5th percentile of the risk estimates of...