Associations of air pollution and greenness with the nasal microbiota of healthy infants: a longitudinal study (Publications)
(SD) PM2.5 level was 17.1 (3.8mug/m(3)) and mean (SD) NO2 level was 19.7 (7.9mug/m(3)). Increased PM2.5 and increased NO2 were associated with reduced within-subject Ruzicka dissimilarity (PM2.5: per 1mug/m(3) [...] long-term respiratory health. We aimed to examine associations between fine particulate matter (PM2.5), nitrogen dioxide (NO2) and greenness with the nasal microbiota of healthy infants during the first [...] d the association of satellite-based greenness and an 8-day-average...
Quantifizierung des Gesundheitsnutzens der neuen Luftqualitätsleitlinien der Weltgesundheitsorganisation in der Schweiz: Projekt GeLuft,... (Publications)
PM2.5 (10 μg/m3) würde die mittlere Einhaltung des WHO-AQG-2021-Werts (5 μg/m3) ca. 3'370 luftverschmutzungsbedingte Todesfälle (35’800 verlorene Lebensjahre) bei Erwachsenen vermeiden. Da die PM2.5-Immissionen [...] utzens für das Jahr 2019 berechneten wir die Gesundheitsauswirkungen der Luftverschmutzung mit PM2.5 und NO2 in einem Referenzszenario (mittlere Exposition in der Bevölkerung, entspricht den WHO-AQG-Werten [...] die Schweiz im Jahr 2019 als Bezugsgrösse. Die gesundheitlichen...
Quantifizierung des Gesundheitsnutzens der neuen Luftqualitätsleitlinien der Weltgesundheitsorganisation in der Schweiz: Projekt GeLuft,... (Publications)
PM2.5 (10 μg/m3) würde die mittlere Einhaltung des WHO-AQG-2021-Werts (5 μg/m3) ca. 3'370 luftverschmutzungsbedingte Todesfälle (35’800 verlorene Lebensjahre) bei Erwachsenen vermeiden. Da die PM2.5-Immissionen [...] utzens für das Jahr 2019 berechneten wir die Gesundheitsauswirkungen der Luftverschmutzung mit PM2.5 und NO2 in einem Referenzszenario (mittlere Exposition in der Bevölkerung, entspricht den WHO-AQG-Werten [...] die Schweiz im Jahr 2019 als Bezugsgrösse. Die gesundheitlichen...
Antitumoral and antileishmanial dioncoquinones and ancistroquinones from cell cultures of <em>Triphyophyllum peltatum</em> (Dioncophyllaceae) and... (Publications)
Dioncoquinones A (4) and B (5) showed good - and specific - activity against Leishmania major, while they were not active against other protozoic parasites. Moreover, treatment with 4 and 5 strongly induced apoptosis [...] and Ancistrocladaceae seven new natural naphthoquinones were isolated, dioncoquinones A (4) and B (5) from Triphyophyllum peltatum, and ancistroquinones B (6), C (7), D (9), E (10), and F (12) from An
Prevalence of four enteropathogens in the faeces of young diarrhoeic dairy calves in Switzerland (Publications)
prevalences of C parvum, rotavirus, BCV and E coli k99 were 55.0 per cent, 58.7 per cent, 7.8 per cent and 5.5 per cent, respectively. The proportions of herds positive for the respective pathogens among the herds [...] 52.1 per cent, 2.1 per cent and 2.1 per cent. The immunoglobulin concentration in the serum of 90.5 per cent of the diarrhoeic calves was below 8 g/l
Antikinetoplastid antimitotic activity and metabolic stability of dinitroaniline sulfonamides and benzamides (Publications)
N(1)-Phenyl-3,5-dinitro-N(4),N(4)-di-n-propylsulfanilamide (1) and N(1)-phenyl-3,5-dinitro-N(4),N(4)-di-n-butylsulfanilamide (2) show potent in vitro antimitotic activity against kinetoplastid parasites [...] potent compounds are rapidly degraded by rat liver S9 fractions in vitro, N(1)-(3-hydroxy)phenyl-3,5-dinitro-N(4),N(4)-di-n-butylsulfanilamide (21) displays an IC(50) value of 260nM against African tr
Antikinetoplastid antimitotic activity and metabolic stability of dinitroaniline sulfonamides and benzamides (Publications)
N(1)-Phenyl-3,5-dinitro-N(4),N(4)-di-n-propylsulfanilamide (1) and N(1)-phenyl-3,5-dinitro-N(4),N(4)-di-n-butylsulfanilamide (2) show potent in vitro antimitotic activity against kinetoplastid parasites [...] potent compounds are rapidly degraded by rat liver S9 fractions in vitro, N(1)-(3-hydroxy)phenyl-3,5-dinitro-N(4),N(4)-di-n-butylsulfanilamide (21) displays an IC(50) value of 260nM against African tr
Antitumoral and antileishmanial dioncoquinones and ancistroquinones from cell cultures of <em>Triphyophyllum peltatum</em> (Dioncophyllaceae) and... (Publications)
Dioncoquinones A (4) and B (5) showed good - and specific - activity against Leishmania major, while they were not active against other protozoic parasites. Moreover, treatment with 4 and 5 strongly induced apoptosis [...] and Ancistrocladaceae seven new natural naphthoquinones were isolated, dioncoquinones A (4) and B (5) from Triphyophyllum peltatum, and ancistroquinones B (6), C (7), D (9), E (10), and F (12) from An
Prevalence of four enteropathogens in the faeces of young diarrhoeic dairy calves in Switzerland (Publications)
prevalences of C parvum, rotavirus, BCV and E coli k99 were 55.0 per cent, 58.7 per cent, 7.8 per cent and 5.5 per cent, respectively. The proportions of herds positive for the respective pathogens among the herds [...] 52.1 per cent, 2.1 per cent and 2.1 per cent. The immunoglobulin concentration in the serum of 90.5 per cent of the diarrhoeic calves was below 8 g/l
Comparative palatability of orally disintegrating tablets (ODTs) of praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: a... (Publications)
analogue scale (VAS) incorporating a 5-point hedonic scale, immediately after spitting out the test product (VASt = 0 primary outcome) and after 2-5 minutes (VASt = 2-5). PRINCIPAL FINDINGS: In total, 48 [...] Higher VASt = 0 and VASt = 2-5 scores were reported for L-PZQ ODT compared with Rac-PZQ ODT in older children (p = 0.046 and p = 0.026, respectively). The VASt = 0 and VASt = 2-5 were higher for both ODT
