A satellite-based spatio-temporal machine learning model to reconstruct daily PM2.5 concentrations across Great Britain (Publications)
matter (PM2.5) levels across Great Britain between 2008–2018. This high-resolution model consists of random forest (RF) algorithms applied in four stages. Stage-1 augments monitor-PM2.5 series using [...] spatial and spatio-temporal variables to build a prediction model for PM2.5. Stage-4 applies Stage-3 models to estimate daily PM2.5 concentrations over a 1 km grid. The RF architecture performed well in all [...] epidemiological analyses to assess health risks associated with both short- and...
Estimating urban <em>PM</em>10 and <em>PM</em>2.5 concentrations, based on synergistic MERIS/AATSR aerosol observations, land cover and morphology... (Publications)
approaches for quantitative estimation of daily mean Particulate Matter (PM) concentrations. Both fine (PM2.5) and coarse (PM10) concentrations were estimated over the area of London (UK) for the 2002–2012 time
Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study (Publications)
BACKGROUND: To prevent child deaths from severe malaria, early parenteral treatment is essential. Yet, in remote rural areas, accessing facilities offering parenteral antimalarials may be difficult. A
Mortality and morbidity effects of long-term exposure to low-level PM2.5, BC, NO2, and O3: an analysis of European cohorts in the ELAPSE project (Publications)
= 1.11, 1.16) for an increase of 5 mug/m(3) PM2.5, 1.09 (CI = 1.07, 1.10) for an increase of 10 mug/m(3) NO2, and 1.08 (CI = 1.06, 1.10) for an increase of 0.5 x 10(-5)/m BC for natural-cause mortality [...] = 1.02, 1.09) for an increase of 5 mug/m(3) PM2.5, 1.04 (CI = 1.02, 1.07) for an increase of 10 mug/m(3) NO2, and 1.04 (CI = 1.02, 1.06) for an increase of 0.5 x 10(-5)/m BC, and 0.95 (CI = 0.93, 0.98) [...] investigate whether the associations persisted below specific concentration values....
Age and cancer incidence in 5.2 million people with HIV: the South African HIV Cancer Match study (Publications)
Using natural splines, we modelled cancer incidence rates as a function of age. RESULTS: We included 5,222,827 PWH with 29,580 incident cancer diagnoses - most commonly cervical cancer (n = 7418), Kaposi
Differential mortality risks associated with PM2.5 components: a multi-country, multi-city study (Publications)
BACKGROUND: The association between fine particulate matter (PM2.5) and mortality widely differs between as well as within countries. Differences in PM2.5 composition can play a role in modifying the effect estimates [...] daily total PM2.5 through time series regression analysis. We then pooled these estimates in a meta-regression model that included city-specific logratio-transformed proportions of seven PM2.5 components as [...] heterogeneity in PM2.5 risk. CONCLUSIONS: These findings...
Immunodeficiency and cancer in 3.5 million people living with Human Immunodeficiency Virus (HIV): the South African HIV cancer match study (Publications)
BACKGROUND: We analyzed associations between immunodeficiency and cancer incidence in a nationwide cohort of people living with human immunodeficiency virus (HIV; PLWH) in South Africa. METHODS: We us
Gesundheitsrisiko Mobilfunkstrahlung? Was ändert sich mit 5G? (Publications)
guideline values. With increasing mobile data usage and the associated use of higher frequencies for 5G, a densification of the mobile network is to be expected. However, this will not necessarily increase [...] the overall RF-EMF exposure of the population, as mobile phones emit less with better signal quality. 5G is a technological advancement of the previous mobile radio technology with the same biophysical properties
The Youth Attitudes about Vaccines (YAV-5) scale: adapting the parent attitudes about childhood vaccines short scale for use with youth in German,... (Publications)
YAV-14 and the YAV-5, but we only report results of the YAV-5 analysis here. We determined construct validity by logistic regression of the association between youth VH as measured by the YAV-5 and non-receipt [...] (PACV-15) for use in youth to create the version Youth Attitudes about Vaccines survey (YAV-14 and YAV-5), then translated it into three languages (German, French, and Italian). We administered the YAV-14 [...] non-immunization in the German-language sample. Our results demonstrate...
Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from <em>Ancistrocladus tanzaniensis</em> (Publications)
naphthylisoquinoline alkaloids, the 7,3'-coupled ancistrotanzanine C (6), the 5,1'-coupled O-methylancistrocladinine (7), and the likewise 5,1'-coupled O,N-dimethylancistrocladine (8, previously known only as a [...] two known 7,3'-coupled naphthylisoquinoline alkaloids ancistrocladidine (4) and ancistrotectorine (5). All of the compounds are S-configured at C-3 and bear an oxygen at C-6, and thus belong to the so-called