Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug... (Publications)
treatments highly ineffective. We have previously shown that the di-amino quinazoline QN254 [5-chloro-N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine] is active against the highly PM-resistant Plasmodium
Inhibitors of adenosine consuming parasites through polymer-assisted N-acylation of N6-substituted 5'-amino-5'-deoxyadenosines (Publications)
A series of 30 adenosine derivatives with three different substituents at the N(6)-position were prepared in order to evaluate their potential to inhibit the pathogenic protozoa Plasmodium falciparum
Comparison of ambient airborne PM2.5, PM2.5 absorbance and nitrogen dioxide ratios measured in 1999 and 2009 in three areas in Europe (Publications)
same pollutants were measured in each campaign (mass concentration of particles =2.5 microns in diameter (PM2.5), PM2.5 absorbance (a marker for black carbon), and NO2) using the same methods except for [...] methods were validated against side-by-side chemiluminescence measurements. The levels of PM2.5 absorbance and PM2.5 were significantly lower (p
Spatial variation of PM2.5, PM10, PM2.5 absorbance and PMcoarse concentrations between and within 20 European study areas and the relationship with... (Publications)
analyses the spatial variation of PM2.5. PM2.5 absorbance, PM10 and PMcoarse concentrations between and within 20 study areas across Europe. We measured NO2, NOx, PM2.5. PM2.5 absorbance and PM10 between October [...] highest average PM2.5 concentrations found in Turin and the highest PMcoarse in Heraklion. Street/urban background concentration ratios for PMcoarse (mean ratio 1.42) were as large as for PM2.5 absorbance (mean [...] those for PM2.5 (1.14) and PM10 (1.23), documenting the...
Development of land use regression models for PM2.5, PM2.5 absorbance, PM10 and PMcoarse in 20 European study areas; results of the ESCAPE project (Publications)
individual exposure for participants of cohort studies. Within the ESCAPE project, concentrations of PM2.5, PM2.5 absorbance, PM10 and PMcoarse were measured in 20 European study areas at 20 sites per area. GIS-derived [...] study area. The median model explained variance (R2) was 71% for PM2.5 (range across study areas 35%-94%). Model R2 was higher for PM2.5 absorbance (median 89%, range 56-97%) and lower for PMcoarse (median